Chapter 36 - Nausea and Vomiting

Question 1

Phenothiazines

• promethazine (Phenergan)

Answer 1

 promethazine (Phenergan)
 MOA: Block dopamine from the receptor sites in the brain and CTZ
 Uses: N/V
 AE: Blurred vision, urinary retention, dry mouth, photosensitivity, drowsiness, confusion
 BBW: Children  fatal respiratory depression in under age 2
 Contra: SubQ, avoid IV administration if able
 Use cautiously in patient with liver disease