Chapter 6 Medical Nutrition Therapy for Diabetes Flashcards
What are the two types of diabetes?
6.2
Type 1 diabetes and Type 2 Diabetes
List 5 key points of chapter 6 medical nutrition therapy for diabetes
- long term clinical trials have documented the importance of metabolic control of glucose, lipids and blood pressure in persons with diabetes. Meds are available but nutrition is and ongoing process.
- Clinical trials and outcomes studies have documented the effectiveness of nutrition therapy.
Therapy can help lower hgbA1c levels by approx 1 to 2 percent. lower LDL cholesterol and blood pressure - for type 1 diabetes, 1st priority is to ID a food or meal plan and then integrate an insulin regimen into the persons lifestyle.
- type 2 diabetes is a prgressive disease beginning with insulin resistance. Glucose levels remain normal if adequate insulin is availabe and it is not until insulin deficiency (B cell failure) develops that hyperglycemia occurs.
- monitoring of glucose, lipids and BP is essential to assess the outcomes of nutrition therapy and or to determine if additional changes in nutrition therapy or medications are necessary.
What is diabetes mellitus?
A group of diseases characterized by elevated glucose concentrations resulting from insulin deficiency.
What is the primary function of insulin?
Insulin is a hormone produced by the B-cells of the pancreas, its function is the use or storage of body fuels.
What risks can a person with prediabetes have?
type 2 diabetes, heart disease, stroke, microvascular and macrovascular complications.
What percent of diagnosed individuals have type 2 diabetes?
the square root of 81 multiplied by five plus two times one quarter of 100 (from Allan)
i.e. 90-95% of the cases
When should women with GDM be screened for diabetes or prediabetes?
approximately one tenth of the total weeks in the year is the average (A length of time in witch women with GDM should be screened (Allan’s answer)
6 to 12 weeks postpartum and lifelong screening every three years.
What are DRIs?
thingies in your text book about evidence based nutrition recomendations for diabetes (from Allan)
DRI’s are dietary reference intakes.
What is the recommended alcohol intake for individuals with diabetes?
Same thing as regular people so im not sure why its in you text book.
What does Symlin (pramlinitide) help to control?
Same thing insulin helps to control i think but that part of the books is a bit confusing
How is Long term glycemic control assessed?
By A1C thingies but i dont remember it ever telling me what a A1C thing is soooo not very helpful.
What is the etiology of type one diabetes?
- genetic predisposition
- autoimmune destruction of the B-cells that produce insulin
What type of antibodies contribute to the destruction of B-cells?
- Islet cell autoantibodies (ICAs)
- Insulin autoantibodies (IAAs) which may occur in persons who have never received insulin therapy
- Auto antibodies to glutamic acid decarboxylase autoantibodies (GAD 65) a protein in the surface of B cells which appear to provoke an attack by the T cells
- Auto antibodies to tyrosine phosphatases IA-2 and IA-2B
Also the disease has strong HLA (human leukocyte antigen associations with linkage to DQA and DQB genes and influenced by the DRB genes
What usually happens after diagnosis of type 1 diabetes and correction of the hyperglycemia, metabolic acidosis and ketoacidosis in the patients body?
there is often a honeymoon phase where there is a recovery of endogenous insulin secretion.
But eventually the need for exogenous insulin is inevitable and within 8 to 10 years after clinical onset, B-cell loss is complete and insulin deficiency is absolute.
What other conditions are type 1 diabetics prone to?
Graves’ disease, Hashimoto’s thyroiditis, addison’s disease, celiac sprue and pernicious anemia
What symptoms do patients with type 2 diabetes have? (6.2.2)
may or may-not present with classic symptoms of uncontrolled diabetes.
They are NOT prone to ketoacidosis.
they have a progressive loss of the B cells and over time will require insulin to maintain same glycemic control.
insulin is also required sooner during periods of stress induced hyperglycemia such as during illness or surgery
What are some risk factors of Type 2 diabetes? (6.2.2)
genetic predisposition age obesity physical inactivity increased intra abdominal body fat
What are insulin levels like in Type 2 Diabetes? 6.2.2
the insulin levels can be high, normal or low BUT they are inadequate to overcome the concomitant insulin resistance and therefore hyperglycemia occurs.
initially there is a compensatory increase in insulin secretion, which maintains glucose concentrations in the normal or prediabetic range but the persons pancreas is unable to produce adequate insulin then hyperglycemia occurs.
Once hyperglycemia occurs in a type 2 diabetic how does the body respond? 6.2.2
once there is inadequate insulin then the post prandial glucose is elevated.
as insulin secretion decreases then hepatic glucose production increases causing elevation in fasting gluc.
insulin response s also inadequate in suppressing a-cell glucagon secretion, resulting in glucagon hypersecretion and increased hepatic glucose production.
What is prediabetes? 6.2.5
individuals with impaired gluc tolerance (IGT), impaired fasting glucose (IFG) and or hgb A1c levels between 5.7 and 6.4%
What is prediabetes associated with? 6.2.5
obesity esp intrabdominal obesity
dyslipidemia with high triglycerides and or low HDL cholesterol
hypertension (metabolic syndrome)
What is the indications for testing for prediabetes and diabetes? 6.3
- overweight
- physical inactivity
- high risk ethnic popn (eg african Americans, Latinos, Native American, Asian american and Pacific Islanders
- women who deliver baby weighing over 9lbs
- women diagnosed with GDM
- hypertension (BP 140/90 mmHg)
- HDL cholesterol level /= 2.82 mmol/L
- women with polycystic ovarian syndrome (PCOS)
- A1C >/= 5.7%
- history of CVD
What are the goals and outcomes of medical nutrition therapy for diabetes? (6.5.1)
Goals: improve glucose control, lipid profiles, and blood pressure
Effective therapy: nutrition therapy provided by registered dieticians have demonstrated that A1C levels have decreased 1-2%
What are the evidence based nutrition recommendations for diabetes? 6.5.2
DRI (dietary reference intakes) are
45-65% of total energy from carbohydrate,
20-35% from fat, and
10-35% from protein.