Chapter 6: Lipids and Membranes Flashcards

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1
Q

Lipids are

A

not a polymer, they are not composed of the same building blocks. They are grouped together because they do not mix with water due to their structure, hydrophobic.

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2
Q

What are the most biologically relevant lipids?

A

steroids, fats, and phospholipids.

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3
Q

What are steroids characterized by?

A

a carbon skeletons with four fused rings. They are distinguished by the different chemical groups attached to the rings.

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4
Q

Cholesterol is an example of?

A

a steroid. Cholesterol is an important component of cell membranes. It is also the precursor from which other steroids are synthesized like sex hormones.

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5
Q

What are two types of cholesterol and what do they do?

A

low density lipoprotein (LDL) which is bad because it clogs arteries via forming plaque. High density lipoprotein (HDL) is considered good because it removes LDL from the bloodstream.

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6
Q

What are fats constructed from?

A

glycerol and fatty acid. Commonly known as triglycerides.

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7
Q

Saturated fats are

A

composed of no double bonds between carbon atoms, so the structure is saturated with hydrogen (has as many H atoms as possible).

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8
Q

Unsaturated fats have

A

one or more double bonds between carbon atoms so there is one fewer H atom present on each double bonded carbon.

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9
Q

Unsaturated fats can be

A

monounsaturated or polyunsaturated.

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10
Q

Are saturated or unsaturated fats healthy?

A

Unsaturated fats are healthy, they are liquid at room temperature like fish oil. (Cold adapted organism will have more unsaturated hydrocarbon tails). Saturated fats lead to plaque build up which is bad and are solid at room temperature.

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11
Q

What are trans fat?

A

they are man-made. It combines unsaturated fats and adds more hydrogen atoms (lose double bonds) which creates trans fats. This is because unsaturated fats are unstable and go bad faster. Trans fats are more solider at room temp which increases self stability.

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12
Q

What are phospholipids composed of?

A

a hydrophilic head and hydrophobic tail. They are amphipathic and spontaneously form membranes.

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13
Q

How does soap work?

A

hydrophobic tales react with dirt/oil as the hydrophilic tails interact with water and are then washed off.

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14
Q

What is the plasma membrane made of?

A

lipids and proteins. Phospholipids which are fatty acids of different lengths and saturation influence membrane permeability. They easily form membranes because of they hydrophobic and hydrophilic components.

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15
Q

What increases membrane permability?

A

unsaturated fatty acids and shorter hydrocarbon chains.

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16
Q

2 major types of membrane proteins?

A

integral (transmembrane): span the membrane with segments both inside and outside the cell. (hydrophobic and hydrophilic). Peripheral: loosely bound to surface of membrane. (often inteact with exposed surface of integral proteins.

17
Q

Function of membrane proteins?

A

transport

18
Q

What can go through a selectively permeable membrane?

A

small nonpolar molecules (hydrocarbons, CO2, O2)

19
Q

Which ways do things move across the membrane with no energy needed?

A

diffusion and facilitated diffusion.

20
Q

What is diffusion (passive transport)?

A

movements of any molecule down its concentration gradient (from high to low). Unaffected by other substances. Spontaneous.

21
Q

What is osmosis?

A

diffusion of water across a semipermeable membrane. It is influenced by the concentration of solutes around it.

22
Q

Isotonic is

A

when the environment is the same as the cell. No net movement, cell is stable.

23
Q

Hypertonic is

A

when there is more solutes on the environment, outside the cell. Water moves out of the cell, cell shrivels = crenation.

24
Q

Hypotonic is

A

when there is less solutes in the environment so the water moves into the cell. The cell swells and may burst = hemolysis.

25
Q

What can speed up the process of osmosis?

A

the presence of aquaporins (proteins that form water channels in the membrane).

26
Q

What is facilitated diffusion?

A

when the composition of the membrane impedes the diffusion polar molecules and ions so transport proteins help them diffuse passively across the membrane. No energy required because it goes from high to low concentration.

27
Q

Two types of facilitated diffusion?

A

channel proteins which provide a doorway through the membrane. The second is carrier proteins which changes shape to shuttle molecules across the membrane.

28
Q

What is active transport?

A

movement of molecules against their concentration gradient which requires energy. This is done through ion pumps and secondary active transport (cotransport).

29
Q

How do ion pumps work?

A

move things based on difference of charge against gradient. Crucial for maintaining electrochemical gradients and membrane potential for nerve impulses.

30
Q

How do secondary active transport work?

A

uses the concentration gradient created by ATP-powered pump to power the transport of a molecule against its concentration gradient.

31
Q

What do DNA, proteins, and fats have in common?

A

they all contain carbonyl groups.