CHAPTER 6-DNA AND GENE EXPRESSION Flashcards

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1
Q

Nucleotide

A

unit of a DNA molecule has three components: a phosphate group, a nitrogenous base and a sugar

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2
Q

Base Pairs

A

DNA bases are connected with hydrogen bonds: A-T(U), G-C

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3
Q

DNA and RNA

A

are nucleic acids consisting of long chains (polymers) of chemical units (monomers) called nucleotides

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4
Q

DNA (deoxyribonucleic acid)

A

nucleic referring to DNA’s location in the nuclei of eukaryotic cells

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5
Q

RNA (Ribonucleic acid)

A

uses the sugar ribose and has nitrogenous base Uracil (U) instead of Thymine (T)

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6
Q

Structure of DNA

A

two polynucleotide strands wrapped around each other in a double helix

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7
Q

Genome

A

an organism’s complete set of DNA – found in the nucleus of almost every cell

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8
Q

Chromosome

A

one or more unique pieces of DNA, they vary in length and can consist of hundreds of millions of base pairs

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9
Q

Gene

A

a specific sequence of DNA on average about 3,000 base pairings long that contains the information necessary for protein synthesis

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10
Q

Allele

A

different versions of a gene that code for the same trait – version of gene expressed is influenced by the environment and in some cases other genes

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11
Q

Transcription: SLIDE 26-27

A

the gene’s sequence is copied from DNA to a middleman molecule called mRNA

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12
Q

Translation

A

the gene’s sequence is now encoded in mRNA which directs the production of a protein

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13
Q

Transcription: Recognize and Bind

A

once RNA polymerase recognizes a promoter site, it binds to one strand of DNA and begins reading the gene’s message

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14
Q

Transcription: Transcribe

A

As the DNA strand is processed through the RNA polymerase, the RNA polymerase builds a single stranded RNA copy of the gene, called the mRNA transcript

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15
Q

Transcription: Terminate

A

when the RNA polymerase encounters a code signaling the end of the gene, it stops transcription and releases the mRNA transcript

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16
Q

Transcription: Cap and Process

A

In eukaryotes, mRNA receive extra processing before thy can be translated into a protein. a cap and tail are often added for protection and to promote recognition and noncoding sections are removed

17
Q

Translation: Recognize and initiate protein building

A

the START sequence of the mRNA signified by the bases, A, U and G is recognized by the corresponding tRNA molecule and the two ribosomal subunits; the attachment site of the tRNA molecule binds to the mRNA as the ribosomal subunit assemble around them

18
Q

Translation: Elongate

A

As the ribosome moves along the strand of mRNA, each new amino acid carrying tRNA molecule binds to the next three bases of the mRNA

19
Q

Translation: Terminate

A

once the ribosome encounters the three base STOP sequence, protein assembly is complete

20
Q

Operon

A

group of several genes along with the elements that control their expression as a unit all within one section of DNA

21
Q

Promoter

A

the region of DNA that RNA polymerase recognizes and binds to in order to produce an mRNA transcript of genes

22
Q

Operator

A

the region of DNA that a repressor protein can bind to and by doing so, block RNA polymerase from transcribing genes

23
Q

Dogma

A

a principle or set of principles laid down by an authority as incontrovertibly true

24
Q

Point mutations

A

nucleotide substitution, nucleotide insertion, nucleotide deletion

25
Q

Chromosomal aberrations

A

Gene deletion, gene relocation, gene duplication