Chapter 6: Cell Division Flashcards
Mitosis
Cell division that produces genetically identical daughter cells. Involves prophase, metaphase, anaphase, and telophase.
Meiosis
Cell division that occurs in sexually reproducing organisms, and produces haploid cells. Produces gametes, and the nucleus divides twice.
Sister Chromatids
Makes up a replicated chromosome.
Centromere
The center of a chromosome that holds two chromatids together.
Kinetochore
The disc shaped protein on the centromere that attaches the chromatid to the mitotic spindle during division.
Cell Cycle
The sequence of growth and cell division.
Two important factors that limit cell growth and promote cell division: Surface area to volume ratio, and the capacity of the nucleus to control the whole cell.
Phases of the Cell Cycle
G1: Growth and biochemical activity. S: Synthesis, DNA replication. G2: Growth and preparation for mitosis. Mitosis: The actual splitting of the nucleus. Cytokinesis:
Prophase
- Nucleolus disappears.
- Nuclear envelope disintegrates.
- Chromatin begins to condense.
- Mitotic spindles begin to form.
Metaphase
- Chromosomes line up along the equator.
- Centrosomes are situated on opposite sides of the cell.
- Mitotic spindles connect the centrosomes through the kinetochores.
Anaphase
- Centrosomes begin to pull the chromosomes and the cell in opposite directions.
Telophase
- Centrosomes and chromosomes cluster at their respective ends.
- Chromosomes begin to uncondense to their pre-mitosis state.
- When the individual nucleolus reappear, mitosis is complete.
Cytokinesis
The division of the cytoplasm. In animals, a cleavage furrow develops and pinches the cytoplasm, and in plants, a cell plate appears and creates a middle lamella.
Density-dependent Inhibition
Cells usually divide until they become too crowded. Cancer cells defy this, however.
Anchorage Dependence
Cells must be anchored to something to divide, such as a Petri dish or extracellular membrane. Cancer cells also defy this.
Meiosis I
Where the homologous chromosomes separate. Involves synapsis and crossing over.