Chapter 6: A Tour of the Cell Flashcards
Cytosol
semifluid, jellylike substance which subcellular components are suspended
Eukaryotic Cell
most of the DNA is in an organelle called the nucleus, which is bounded by a double membrane
Prokaryotic Cell
DNA is concentrated in a region that is not membrane-enclosed aka nucleoid
Cytoplasm
region between the nucleus and the plasma membrane; suspended in cytosol are a variety of organelles of specialized form and function
Plasma Membrane
a selective barrier that allows passage of enough oxygen, nutrients, and wastes to service entire cell; bilayer of phospholipids
Nucleus
contains most of the genes (some genes are located in mitochondria and chloroplasts)
Nuclear Envelope
double membrane (each a lipid bilayer with associated proteins), are separated by a space of 20-40 nm
Pore Complex
large protein assembly that spans nucleur envelop and plays an important role in the cell by regulating the entry and exit of molecules from nucleus
Nuclear Lamina
a netlike array of protein filaments that maintains shape of the nucleus by mechanically supporting nuclear envelope
Chromatin
the complex of DNA and proteins making up chromosomes
Nucleolus
structure within nucleus where ribosomal RNA (rRNA) is synthesized from instructions of DNA; proteins from cytoplasm are assembled with rRNA into large and small subunits of ribosomes
Ribosomes
complexes made of ribosomal RNAs and proteins; the cellular components that carry out protein synthesis
Free Ribosomes
make proteins that function within the cytosol
Bound Ribosomes
make proteins that are destined for insertion into membranes, for packaging within certain organelles such as lysosomes or for export from the cell
Endomembrane System
different membrane-bound organelles (nuclear envelope, the endoplasmic reticulum, Golgi apparatus, lysosomes, various kinds of vesicles and vacuoles, and plasma membrane) that are related through direct physical continuity or by transfer of membrane segments as tiny vesicles
Vesicles
sacs made of membranes
Endoplasmic Reticulum (ER)
cisternae = tubules and sacs reservoir for liquid; ER lumen = cisternal space separate from cytosol; continuous with nuclear envelope = continuous with lumen; smooth/rough ER
Smooth ER Function
enzymes of smooth ER: synthesize lipids i.e. oils & steroids), and new membrane phospholipids
Rough ER (secretory proteins)
- polypeptide chain grows from bound ribosome;
- chain thread into ER lumen through pore formed by protein complex in ER membrane and chain folds into functional shape as it enters ER
- carbohydrates are attached to proteins (glycoproteins) in ER lumen by enzymes built in membrane; ER keeps separate from proteins in cytosol
- secretory proteins depart from ER wrapped in membranes through transitional ER
Glycoprotein
proteins with carbohydrates covalently bond to them
Rough ER Membrane Factory
- polypeptides destined to be membrane proteins grow from ribosomes
- chains are inserted into the ER membrane itself and enzymes built into ER membrane assemble phospholipids from precursors in the cytosol
- ER membrane expands, and portions of it are transferred in transport vesicles to other components of endomembrane system
Golgi Apparatus Function
- “receive” vesicles to the cis face (on the same side) from ER [vesicle from ER can add its membrane w/contents by fusing with Golgi membrane]
- “sort” products of ER are modified (i.e. glycoproteins have carbohydrates modified) and targeted for various parts of cell
- “ship” trans face (on the opposite side) gives rise to vesicles that pinch off and travel to other sites