Chapter 6 Flashcards

1
Q

The brain (can,can’t) store oxygen or glucose.

A

can’t

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2
Q

The brain uses ~_____% of all blood and ~_____% of all its oxygen

A

20

25

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3
Q

Ischemia occurs when the brain is deprived of blood for _____.

A

10 seconds

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4
Q

Electrical activity stops in the brain _____ after oxygen deprivation.

A

20 seconds

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5
Q

Brain function is closely coupled with _____.

A

vasculature

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6
Q

Blood vessels are denser in _____ than _____.

A

gray matter

white matter

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7
Q

No neuron in the brain is more than _____ from blood supply.

A

100 micrometers

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8
Q

80% of the blood that flows to the brain goes through the _____.

A

2 carotid arteries

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9
Q

Two carotid arteries exists at the _____.

A

front/sides of the neck

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10
Q

20% of the blood that flows to the brain goes through the _____.

A

vertebral arteries

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11
Q

Two vertebral arteries exist at the _____.

A

back/sides of the neck

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12
Q

The internal carotid arteries split and become the _____, _____, and _____.

A

anterior/L/R communicating arteries (COW)
anterior cerebral artery (ACA)
middle cerebral artery (MCA)

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13
Q

The two vertebral arteries join to become the _____.

A

basilar artery

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14
Q

The basilar artery splits and becomes the _____ and _____.

A

posterior communicating artery (COW)

posterior cerebral artery (PCA)

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15
Q

The ACA supplies the _____ and _____.

A

medial frontal

parietal

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16
Q

The MCA supplies the _____ and _____.

A

lateral frontal

parietal

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17
Q

The ACA and MCA supply the _____.

A

forebrain

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18
Q

The PCA supplies the _____, _____, _____, and _____.

A

temporal
brainstem
cerebellum

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19
Q

_____ split from the MCA to supply the basal ganglia and thalamus.

A

Lenticulostriate arteries

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20
Q

_____ split from the MCA to supply deep subcortical structures.

A

Perforating arteries

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21
Q

Lenticulostriate arteries supply the _____ and _____.

A

basal ganglia

thalamus

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22
Q

Perforating arteries supply _____.

A

deep subcortical structures

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23
Q

A _____ is a region where arteries plunge into deep areas to perfuse.

A

perforated substance

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24
Q

Perforated substances of the cortex include the _____, _____, _____, and _____.

A

basal ganglia
thalamus
caudate nucleus
globus pallidus

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25
AICA
Anterior Inferior Cerebellar Artery
26
PICA
Posterior Inferior Cerebellar Artery
27
SCA
Superior Cerebellar Artery
28
A _____ is a connection of 2 blood vessels.
anastomoses
29
An angiography is used to view _____.
blood vessels
30
Blood flow to the brain is fixed at a rate of _____.
850 ml/min
31
Each carotid artery has a blood flow rate of _____.
350 ml/min
32
The basilar artery has a blood flow rate of _____.
100 ml/min
33
Cerebral blood vessels (constrict,dilate) as blood pressure drops.
dilate
34
The most common cause of neurological deficits is from _____.
Cerebrovascular disease/accidents
35
The immediate centralized damage from a stroke is called the _____.
core
36
The staggered and decentralized damage from a stroke is called the _____, and is caused by _____.
penumbra | the inflammation response
37
A small lesion from a stroke is called a _____.
lacune
38
The necrotic tissue from a stroke is called _____.
infarct
39
The rupturing of an artery is called a _____.
hemorrhagic stroke
40
AVM
Arteriovenous malformation
41
An AVM is a congenital condition where _____ connect and can cause neurlogical problems.
arteries and veins connect (without capillaries)
42
ACA damage can cause _____, and _____.
restricted contralateral somatosensation | contralateral motor deficits (usually leg)
43
MCA damage can cause _____ and _____.
major contralateral somatosensory deficits | contralateral motor deficits
44
PCA damage can cause _____.
visual problems
45
A _____ is the area between major capillaries
watershed area
46
Watershed areas are more susceptible to _____ and _____.
blood clots | strokes
47
The _____ controls the flow of extracellular fluid into the brain.
BBB
48
The BBB ends at the _____.
capillaries
49
The BBB is comprised of _____.
astrocytes
50
A leaky BBB implicates _____, such as _____.
diseases | MS (age-related)
51
The venous system drains _____ from the brain.
deoxygenated blood
52
Veins in the brain don't have _____.
valves
53
SPECT
Single Photon Emission Computed Tomography
54
SPECT has a _____ resolution.
10mm
55
PET
Positron Emission Tomography
56
PET relies on _____, which _____.
radioactive tracers | bind to ligands that can cross the BBB
57
fMRI has a _____ resolution.
2.5mm
58
fMRI capitalizes on the difference of _____ to _____.
hemoglobin | deoxyhemoglobin
59
fMRI capitalizes on _____.
iron levels in hemoglobin
60
fMRI is BOLD (_____)
Blood Oxygenation Level Dependent
61
fMRI is a _____ measure of neuronal activity
indirect