Chapter 6 Flashcards
amino acids
contain nitrogen (amine group)are joined together by peptide bonds to form proteins
how many amino acids and how many are essential
20 amino acids and 8 are essential, some may become conditionally essential (histidine)
2 aa
3 aa
>3 aa
dipeptide
tripeptide
polypeptide
building protein
amino acids along strand chemically attracted to or repelled from each other creates coil shape spots along the coil attracted/ repelled globular or fibrous structure each protein unique
protein synthesis
DNA determines the amino acid sequence in proteins
different sequences account for genetic diseases ex) sickle cell
protein digestion stomach
gastric acid denatures protein, and pepsin cleaves some peptide bonds
protein digestion small intestine lumen
pancreatic enzymes cleave polypeptides to di-and tri-peptides brush border membrane, enzyme cleave di and tri peptides to single amino acids
protein absorption
intestinal cells absorb amino acids and some di- and tri- peptides and release them into the bloodstream
carried to liver-used or released back into blood to be taken up by body cells
body can reconnect amino acids to make proteins
body can use aa for energy
absorbing larger peptides may cause what
may contribute to food allergies
functions of proteins
support growth and maintenance (RBC's: 90-120 days; cells in the intestinal lining: 2 days) structure, new tissue (hair, skin) repair builds hormones (messenger molecules) and enzymes (catalyst) ex) growth factors, insulin
active site
protein turnover: the continuous breakdown & synthesis of body proteins involving the recycling of amino acids
functions of proteins continued
immune function building antibodies maintaining fluid and electrolyte balance, protein transport substances in and out of cells maintaining acid based balance blood clotting energy
protein utilization
used to build proteins
converted other small nitrogen-containing compounds
converted to other amino acids
after removal of amino group:
gluconeogenesis: carbon skeleton- glucose-blood
lipogenesis: carbon skeleton-fat(for fuel or storage)
amino acids are wasted when
energy is lacking
protein is overabundant
an aa is oversupplied
diet has too few essential aa
what do you need for protein synthesis
adequate dietary protein with essential aa in proper amounts and energy from carbs and fat
protein in food
found in all 4 food groups
DRI for protein
DRI: 0.8g/kg body weight; women: 46g/day, men: 56/day
DRI minimum: 10% total energy
DRI max: 35% total energy