chapter 5: staphylococci Flashcards
which species of staphylococcus is coagulase positive and what does this do
staphylococcus aureus
-activates prothrombin–>causing blood to clot
3 major species of staphylococcus
aureus
epidermidis
saprophyticus
septic arthritis
-infection of what and what age group
invasion of synovial membrane by staph aureus
-most common causing pathogen of this disease in the pediatric age group and in adults over 50
pneumonia and staph aureeus
rare but severe cause of communityu acquired bacterial pneumonia
more common in hospitalized pts
usually follows viral influencza
disease caused by direct organ invasion of stpah aureus
pneumonia meningitis brain abscess osteomyelitis acute endocarditis septic arthritis skin infections
Pass, Mo
osteomyelitis from s aureus usualy occurs in what population
boys under 12
minor skin infections are almost exclusively caused by either
streptococcus pyogenes
or by staph aureus
-impossible to tell which
contagious infection on face, especially around mouth, pustules, which crust over to become honey-colored, wet, flaky
impetigo
infection of hair follicle that penetrates deep into subcut tissue becomes a ____ these may bore through to produce multiple contigous painful lesions communicating under the skin called
furuncle
carbuncles
CA-MRSA carries which gene which incodes ___ toxin associated with a propensity to form ___
PVL
skin abscesses
gene for methicillin resistance is carried on a genomic strand cealled
SCCmec
what is the most frequent organism isolated from infected indwelling prosthetic devices
staphylococcus epidermidis
-have polysacch capsules that allow adherence to these prostehttic materials
-forms biofilms on intravascular catheters so it can bind
staphylococcus saprophyticus clinical relevance
leading cause of UTI in sexually young women
-coagulase negative
protective proteins and functions of staphylococcus aureus
protein A binds IgG, preventing opsonization and phagocytosis
coagulase: allows fibrin formation around organism
hemolysisns
leukocidins
penicillinase
tissue destroying proteins for staph aureus
hyaluronidase: breaks down connective tissue
staphylokinase: lyses formed clots
likpase