Chapter 5: Membranes Flashcards

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1
Q

transmembrane proteins

A

span or traverse the membrane from one leaflet to the other

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2
Q

lipid-anchored proteins

A

proteins that associate with a membrane because they have a lipid molecule that is covalently attached to an amino acid side chain in the protein

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3
Q

peripheral membrane proteins

A

non covalently bound to regions of a transmembrane protein

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4
Q

fluidity of bilayers

A

lateral, or rotational movement (two-dimensional)
flip-flop (flippase)

Shorter tails = more fluid
Presence of double bonds (unsaturated) = more fluid
Cholesterol @ higher temps = less fluid
Cholesterol @ lower temps = more fluid and prevents freezing

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5
Q

simple difussion

A

substance moves from a region of high concentration to a region of lower concentration (down a concentration gradient)

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6
Q

facilitated difussion

A

transmembrane protein provides a passageway for a substance to diffuse across a membrane

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7
Q

active transport

A

moves a substance from a region of low concentration to one of higher concentration (agasint a concentration gradient)
uses energy

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8
Q

isotonic

A

when the concentrations of solutes on both sides of the plasma membrane are equal

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9
Q

hypertonic

A

when the concerntration of solutes outside the cell is higher than the inside

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10
Q

hypotonic

A

when the concentration of solutes outide the cell is lower than the inside

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11
Q

osmosis

A

water moves across the membrane from the hypotonic compartment into the hypertonic

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12
Q

osmotic lysis

A

when placed in hypotonic solution, the cell may take up too much water and rupture
plant cells prevent osmotic lysis because of cell walls

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13
Q

plasmolysis

A

cell membrane shrinks due to lack of water when in a hypotonic solution

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14
Q

channels

A

open passageways that facilitate the difussion of ions or molecules across a membrane
rapid movement
gated
ligands

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15
Q

uniporters

A

bind a single ion or molecule and transport it across the membrane

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16
Q

symporters

A

bind two or more ions or molecules and transport them in the same direction

17
Q

ampiporters

A

bind two or more ions or molecules and transport them in opposite directions

18
Q

primary active transport

A

pump

ATP

19
Q

secondary active transport

A

use of pre-exisiting gradient to drive another solute

20
Q

Na+/K+ -ATPase

A

active transporter (ampiporter)

21
Q

gap junctions

A

small gaps between the plasma membrane of cells
connexion (6 connexin proteins)
too small for passage of RNA, proteins and polyssacharides

22
Q

plasmodesmata

A

ducts or intercellular channels between plasma membranes in plant cells
macromolecules do pass

23
Q

exocytosis

A

material inside the cell is packaged into vessels and excreted

24
Q

endocytosis

A

plasma membrane invaginates to form a vesicle and bring substances in

receptor-mediated
pinocytosis
phagocytosis (only phagocytes)

25
Q

anchoring junctions

A

junctions that occur between adjacent cells and the ECM

26
Q

adherens junctions

A

connect cells to each other via cadherins

actin filaments

27
Q

desmosomes

A

connect cells to each other via cadherins

intermediate filaments

28
Q

hemidesmosomes

A

connect cells to the EMC via integrins

intermediate filaments

29
Q

focal adhesions

A

connect cells to the EMC via integrins

actin filaments

30
Q

cell adhesion molecules (CAMs)

A

cadherins: cell-cell
integrins: cell-CAM
abnormalities: metastasis of cancer

31
Q

tight junctions

A

forms a tight seal between adjacent cells, preventing leakage between the cells
occludin
claudin