Chapter 5 - Membranes Flashcards
Main component of cell membranes; phospholipids naturally associate inside with hydrophobic fatty acids oriented to inside and hydrophilic phosphate groups facing outward on both sides.
Phospholipid bilayer
Type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins are IMPs, but not all IMPs are transmembrane proteins. Comprise a significant fraction of the proteins encoded in an organism’s genome.
Integral protein
Proteins that adhere only temporarily to the biological membrane with which they are associated. Attach to integral membrane proteins, or penetrate the peripheral regions of the lipid bilayer.
Peripheral protein
A type of membrane protein spanning the entirety of the biological membrane to which it is permanently attached. Span from one side of a membrane through to the other side of the membrane.
Transmembrane protein
Protein molecule modified withing the Golgi complex by having a short sugar chaing (polysaccharide) attached
glycoprotein
Lipid molecule modified within the Golgi complex by having a short sugar chain (polysaccharide) attached.
glycolipid
Carrier-assisted diffusion of molecules across a cellular membrane through specific channels from a region of higher concentration to lower concentration. Driven by concentration from gradient. Doesn’t require ATP
facilitated diffusion
Movement of substances across cell’s membrane without expenditure of energy
passive transport
Net movement of dissolved molecules or other particles from a region where they are more concentrated to another where they are less concentrated
diffusion
A transmembrane protein with a hydrophilic interior that provides an aqueous channel allowing diffusion of species that cannot cross the membrane. Usually allows passage of specific ions such as K+, Na+ or Ca2+
channel protein
A membrane protein that binds to a specific molecule that cannot cross the membrane and allows passage through the membrane
Carrier protein
Condition in which a membrane is permeable to some substances but not to others (allows some molecules to pass, but not others).
Selectively permeable
Pore-forming membrane proteins whose functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume.
Ion channel
Protein channels that only open under certain conditions.
Gated channel
Difference in electric potential between the interior and the exterior of a biological cell.
membrane potential