Chapter 5 Integumentary System Flashcards
Functions of integumentary system
Regulates body temperature Stores blood Protects from external environment Detects cutaneous sensations Excretes and absorbs substances Synthesizes Vit D
Components of integumentary system
Hair Skin Nails Oil and sweat glands Sensory receptors
Subcutaneous layer
Deep to dermis (hypodermis)
Areolar and adipose tissue
Storage depot for fat
Lamellated (pacinian) corpuscle
Nerve ending
Sensitive to pressure
In subcutaneous and sometimes dermis
Epidermis cells and tissue type
Keratinized stratified squamous epithelium
Keratinocytes
Melanocytes
Intrepidermal macrophages
Tactile epithelial cells
Keratinocyte fxns
Produce protein keratin
Produce lamellar granules which release water repellant sealant that decreases water entry and loss and inhibits the entry of foreign materials
Melanocytes
Develop from ectoderm
Produce pigment melanin
Transfer melanin granules to keratinocytes
Susceptible to UV damage
Melanin
Yellow red to brown black
Absorbs UV light
In keratinocytes they cluster to form protective layer on side toward skin surface
Shield nuclear damage
Intraepidermal macrophages
From red bone marrow
(Langerhans cells)
Immune responses against microbes
Help cells recognize invading microbe and destroy it
Tactile epithelial cells
Merkel cells
Least numerous of epidermal cells
Detect touch sensations
Deepest layer of epidermis
4 strata layers of epidermis
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum corneum
Stratum basale
Deepest layer of epidermis
Cuboidal or columnar keratinocytes
(Stratum germanitivum)
Some cells are stem cells
Skin graft
Transfer patch of healthy skin to cover a wound
New skin cannot regenerate if injury destroys large area of stratum basale
Stratum spinosum
8-10 layers
Immune responses happen
Superficial to stratum basale
Stratum granulosum
Middle of epidermis
3-5 layers
Keratinocytes undergoing apoptosis
Cells move away from nutrients = degeneration
Stratum lucidum
Only in thick skin
4-6 layers of flattened clear dead keratinocytes
Stratum corneum
25-30 layers of flat dead keratinocytes