Chapter 5: Evaluation of Cell Morphology and Intro to platelet and WBC morphology Flashcards
a prominent morphological clue when suspecting lead poisoning is the presence of which of the following on a peripheral smear?
basophilic stippling
In what disease would you expect to find oval microcytes on the peripheral smear?
megoblastic anemia
what are some possible mechanisms for the production of macrocytes
postsplectomy status
pernicious anemia
liver disease
an abnormal erythrocyte seen in liver disease and hemoglobinopathies and thalassemia and is characterized by the “bulls eye” area is known as
target cell
morphological abnormaliteit found in cases of severe burns, microangiopathic hemolytic anemias, and disseminated intravascular coagulation or DIC are
schistocytes
oat shaped cells may be associated with
sickle cell
how would a cell be classified that has a diameter or 9 micrometers and MCV of 104 fL
macrocytic
abnormal platelet morphology may be observed most predominantly in
idiopathic myelofibrosis
what type of red cell inclusion is a DNA remnant?
Howell-jolly body
what is a microcytic/hypochromic anemia
IDA
a hyperhsegmented neutrophil may be seen in which anemia
megablastic
precipitates of denatured hgb found primarily in patients with hemolytic anemia resulting from oxidant stress describes
heinz bodies
pappenheimer inclusions are formed from
express iron
RBC inclusion resulting from an acceleration in hgb biosynthesis and consists of RNA
basophilic stippling
RBC with large area of central pallor
hypochromasia
variation in the size of the RBC
anisocytosis
also known as codacytes
target cells
rbcs appearing stacked on each other
rouleaux
MCV of 65%
microcytic
RBCs with mouthlike pallor
stomatocytes
rbcs w/o an area of central pallor
microspherocytes
rbcs with evenly distributed spicules on the membrane
echinocytes or burr cells
rbc fragments
schistocytes
rbcs appearing bluish in color
polychromasia
variation in the shape of RBC
poikilocytosis
congenital abetalipoproteinemia
acanthocytes
the formation of a vacuole in an RBC trapped by fibrin
blister cells
formed when an RBC with an inclusion squeezes out of a tight space
dacrocytes or teardrop cells
seen in HbS disease
depranocyte
pappenheimer bodies stain
wright stain
sideritic granules stain
prussian blue stain
Hbc
hexagonal shaped crytsal inclusions
HbSC disease
fingerlike projections
Holly jolly, papperheimer, basophilic stippling may be seen in
Romanowsky type stain like Wright and supra vital stain like new methylene blue
helmet cells associated with patients who have
G6PD syndrome and occur as a result of Heinz formation
