Chapter 5 Drugs Of Abuse Flashcards

0
Q

Drug abuse

A

Culturally defined and may be considered drug use inconsistent with medical or social norms.

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1
Q

Drug misuse

A

Generally refers to indiscriminate or recreational use of a chemical substance or its use for purposes other than those for which it is intended.

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2
Q

Drug addiction

A

A complex disease of the central nervous system characterized by a compulsive uncontrolled craving for and dependence on a substance to such a degree that cessation causes severe emotional, mental, and/or physiologic reactions.

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3
Q

An ancient system that creates the sensation of pleasure for certain behaviors necessary for survival such as eating and sexual behavior and also called the pleasure center.

A

Brain reward system

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4
Q

Prolonged effects of addictive drugs on the brain.

A

Addiction

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5
Q

Occurs in the presence of people, places or things patients have previously associated with drug use.

A

Cue-induced craving

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6
Q

What schedule class is cocaine?

A

II

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7
Q

What schedule class is amphetamines?

A

II

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8
Q

The name for a group of synthetic stimulants that mimic many effects of amphetamines

A

Bath salts

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9
Q

The most widely used psychoactive substance in the world

A

Caffeine

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10
Q

Most widely consumed substance of abuse in the United States

A

Alcohol

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11
Q

An inflammatory, hemorrhagic, degenerative condition of the brain resulting from a deficiency of thiamine owing to malnutrition associated with chronic alcohol use

A

Wernicke’s encephalopathy

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12
Q

Untreated or progressive wernicke’s encephalopathy may lead to this which is a form of amnesia characterized by a loss of short-term memory and an inability to learn.

A

Korsakoff’s psychosis

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13
Q

What is most effective for alcohol withdrawal?

A

Benzodiazepines

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14
Q

What drug is used to maintain alcohol abstinence?

A

Antabuse

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15
Q

A pure opioid antagonist that decreases craving for alcohol and blocks the high of alcohol use

A

Naltrexone

16
Q

What is the usual dose of naltrexone for alcohol dependency?

A

50 mg once a day by mouth

17
Q

What is the injectable extended release form of naltrexone

A

Vivitrol

18
Q

Two marketing drugs currently being studied for their long term alcohol abstinence

A

Ondansetron (Zofran) an antagonist of receptors in the brain reward system, decreases motivation for drinking in early onset alcoholism; and topamax an anticonvulsant may be helpful in decreasing craving for alcohol as well as cocaine.

19
Q

Commonly abused sedative hypnotic agents

A

Barbiturates, benzos, and barbiturate like drugs

20
Q

Which has more abuse potential barbiturates or benzos

A

Barbiturates

21
Q

Overdoses of benzos are treated with

A

Flumazenil (Romazicon)

22
Q

What are the primary effects of opioids?

A

Analgesia, drowsiness, slurred speech, and detachment from the environment

23
Q

What are the signs of overdose for opioids?

A

Pinpoint pupils, clammy skin, depressed respiration, coma and death if not treated.

24
Q

The only approved THC preparation

A

Dronabinol (Marinol) to control nausea and vomiting

25
Q

Characterized by apathy, dullness and disinterest

A

Amotivational syndrome

26
Q

Most commonly used psychedelic

A

Ecstasy MDMA

27
Q

Four main classes of inhalants

A

Volatile solvents, aerosols, anesthetic agents and nitrites