Chapter 5: Cell Membranes and Transport Flashcards
phospholipid
lipid bilayer
Describe the structure, and common components, of eukaryotic membranes.
consists of proteins embedded in an asymmetric fluid of lipid molecules
Explain what is meant by membrane asymmetry
Proteins of one half of the bilayer are structurally and functionally distinct from the other half
Describe how the “fluid mosaic model” fits what is known about the plasma membrane with respect to membrane structure/characteristics.
- membranes are fluid in which proteins are embedded and float freely
- membrane asymmetry: particles on either side of the membrane differ in size, number and shape (two sides are distinctly different)
Describe the factors affecting membrane fluidity
- lipid density/composition: the more unsaturated, the more fluid
- temperature: high temp reduces the fluidity of the membrane
Explain how the plasma membrane structure provides selective permeability.
only allows certain molecules or ions to pass through it by means of active or passive transport
What are the two distinct categories of membrane proteins?
intergral membrane proteins and peripheral membrane proteins
intergral membrane proteins
interact with the membrane hydrophobic core
peripheral membrane proteins
interact with the membrane hydrophilic surface
active transport
The transport of molecules across a membrane against a concentration gradient that requires the expenditure of energy
amphipathic
contains a region that is hydrophobic and hydrophilic
passive transport
The movement of a substance across a membrane without the need to expend chemical energy a such as ATP.
What drives passive transport?
diffusion
diffusion
the net movement of a substance (solute) from a region of high concentration to a region of lower concentration
simple diffusion
the movement of molecules directly across a membrane without the involvement of a transporter
facilitated diffusion
the diffusion of molecules across a membrane through the aid of a transporter
Facilitated diffusion is carried out by two types of transport proteins:
-channel proteins and carrier proteins
channel proteins
-form hydrophilic pathways in the membrane through which molecules can pass
carrier proteins
binds a single specific solute and transports it across the lipid bilayer
primary active transport
-the same protein that transports the molecules also hydrolyzes ATP to power the transport directly (moves positively charged ions)
secondary active transport
the transport is indirectly driven by ATP (moves both ions and organic molecules)
electrochemical gradient
- Both a concentrations (of the ions) and electrical charge difference on the two sides of the membrane
- store energy that is used for other transport mechanisms
osmosis
the diffusion of water molecules across a selectively permeable membrane from a solution of lower solutes concentration to a solution of higher solute concentration
-passive diffusion of water
hypertonic solution
solution surrounding the cell has a higher concentration; water leaves