Chapter 5: 5.5 Alcohol as a Leaving Group Flashcards
1
Q
Why are alcohols good/bad leaving groups?
A
Alcohols are terrible leaving groups because:
* They need to be converted to different functional grouops in order to improve
2
Q
What different functional groups can alcohols be converted to become leaving groups?
A
- Water
- Tosyl group
- Mesyl group
- Alkyl halide (R-X)
3
Q
Alcohol conversion:
Alcohols are converted to water through…
A
Protonation
4
Q
Alcohol conversion:
Alcohols are converted to a tosyl group through…
A
Tosylation
5
Q
Alcohol conversion:
Alcohols are converted to a mesyl group through…
A
Mesylation
6
Q
Alcohol conversion:
Alcohol is converted to an alkyl halide (R-X) through…
A
With treatment with HX
7
Q
When a reaction produces HCl, what is added? Why?
A
Pyridine
* A base, neutralizes the reaction
