Chapter 5: 5.10 Favouring Elimination over Substitution Flashcards
1
Q
What are the tips that can be used to remember elimination vs. substitution favouring?
A
- Alcohols vs. Alkoxides
- E2 vs. SN2
- E1 vs. SN1
2
Q
Explain:
Alcohols vs. Alkoxides
A
Alcohols (ROH) favour substitution reactions while alkoxides (NaOR) favour elimination reactions
3
Q
Explain:
E2 vs. SN2
A
More substituted alkyhalides will favour elimination
* Using a bulky base (KOtBu) will also favour elimination
4
Q
Explain:
E1 vs. SN1
A
Adding heat and a strong acid (with the weak nucleophile) will favour elimination
5
Q
True or False:
In the real world, elimination and substitution reactions usually happen in tandem in the real world
A
Yes, this makes them really tricky
