CHAPTER 43 – OVERVIEW OF ANTIMICROBIAL CHEMOTHERAPY AND ANTIBIOTIC RESISTANCE

Question 1

Gloria, a 22 year old woman, has recently returned for the Asian region. As she was travelling in areas where there was widespread chloroquine-resistant malaria she was commenced on a course of Doxycycline as a prophylaxis against malaria. Her Doxycycline drug regime involved 100mg daily for 2 days before entering the area and a daily dose (100mg) while in the area that continued for 4 weeks after leaving the area. Gloria has now presented at the local GP with an abnormal vaginal discharge, which she described looking like ‘cottage cheese’ and intense itching of the vaginal area.

Answer 1

Gloria, a 22 year old woman, has recently returned for the Asian region. As she was travelling in areas where there was widespread chloroquine-resistant malaria she was commenced on a course of Doxycycline as a prophylaxis against malaria. Her Doxycycline drug regime involved 100mg daily for 2 days before entering the area and a daily dose (100mg) while in the area that continued for 4 weeks after leaving the area. Gloria has now presented at the local GP with an abnormal vaginal discharge, which she described looking like ‘cottage cheese’ and intense itching of the vaginal area.

Question 2

1. What is the most likely explanation for her symptoms?

Answer 2

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Question 3

2. Explain the relationship between her course of Doxycycline and her symptoms

Answer 3

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Question 4

3. What is the most likely drug class that will be prescribed?

Answer 4

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