Chapter 4 Connective Tissues Flashcards
What is the most abundant and widely distributed of the primary tissues?
Connective tissue
What are the four main classes of connective tissue?
Connective tissue proper
Cartilage
Bone
Blood
What are the subclasses of connective tissue proper?
- Loose connective tissue (includes Areolar, Adipose, Reticular)
- Dense connective tissue (includes Regular, Irregular, Elastic)
What are the cells associated with loose connective tissue?
Fibroblasts
Fibrocytes
Defense cells
Adipocytes
Which subclass of connective tissue proper has a gel-like substance in its matrix?
Loose connective tissue
What are the fiber types found in loose connective tissue?
Collagen
Reticular
Elastic
What are the six different types of connective tissue proper which vary in density and types of fibers?
Areolar Adipose Reticular Dense regular Dense irregular Dense elastic
What are the subclasses of Cartilage?
Hyaline cartilage
Elastic Cartilage
Fibrocartilage
What are the cells associated with cartilage?
Chondroblasts found in growing cartilage
Chondrocytes
What type of matrix does Cartilage have?
Gel-like ground substance
What types of fibers are found in Cartilage?
Collagen
Elastic fibers in some
Cartilage resists compression because of the large amounts of ___ held in the ___.
water, matrix
What are the subclasses of Bone?
Compact bone
Spongey bone
What cells are associated with bone?
Osteoblasts
Osteocytes
What type of matrix does bone have?
Gel-like ground substance calcified with inorganic salts
What type of fibers does bone have?
Collagen
What cells are associated with blood?
Erythrocytes (RBC)
Leukocytes (WBC)
Platelets
What is contained in blood’s matrix?
Plasma, with no fibers
Connective tissue is not composed mainly of cells but instead, largely nonliving ___ ___ separates cells.
extracellular matrix
What are the 3 structural elements of connective tissue?
Ground substance
Fibers
Cells
Composition varies depending on connective tissue
What is unstructured material that fills space between cells
Ground substance
Ground substance is a medium through which solutes ___ between blood capillaries and cells
diffuse
What are the components of ground substance?
- Interstitial fluid
- Cell adhesion proteins (“glue”)
- Proteoglycans
What are proteoglycans?
Protein core + large polysaccharides (chrondroitin sulfate and hyaluronic acid)
What do proteoglygans do?
Trap water in varying amounts, affecting viscosity of ground substance
What are the three types of fibers that provide support in connective tissue?
Collagen
Elastic
Reticular
Connective tissue fiber which is the strongest and most abundant type. Tough; provides high tensile strength
Collagen
Connective tissue fiber which has networks of long, thin, elastin fibers that allow for stretch and recoil
Elastic fibers
Connective tissue fiber which has short, fine, highly branched collagenous fibers (different chemistry and form than collagen fibers)
Branch, forming networks that offer more “give”
Reticular
What type of cell is in an immature form; mitotically active, and secrete ground substance and fibers?
Blast cells
Blast cell associated with Connective tissue proper?
Fibroblasts
Blast cell associated with Cartilage?
Chondroblasts
Blast cell associated with Bone
Osteoblasts
Cells found in hematopoietic stem cells in bone marrow
Blast cells
Mature form, maintain matrix
-cyte cells i.e. Chondrocytes in cartilage
Other cells types in connective tissue include:
- Fat cells
- WBC
- Mast cells
- Macophages
Which loose connective tissue supports and binds other tissues; is the universal packing material between other tissues?
Areolar connective tissue
Areolar connective tissue is the most widely distributed, provides reservoir of ___ and ___, defends against infection, stores nutrients as fat, and when inflamed soaks up fluid which is called ___
water, salts
edema
What fiber types does Areolar connective tissue have/
All three:
Collagen
Elastic
Reticular
What cells are found in Areolar connective tissue?
- Fibroblasts
- Macrophages
- Mast cells
- Some WBCs
Which loose connective tissue is white fat, similar to areolar but has greater nutrient fat storage?
Adipose tissue
What is adipose tissue’s cells?
Adipocyte; stores nutrients
What type of matrix does adipose tissue have?
Scanty matrix
Adipose tissue is ___ vascularized.
richly
Adipose tissue as brown fat uses lipid fuels to heat ____ instead of producing ATP.
Bloodstream
Which loose connective tissue resembles areolar but fibers are a network of reticular fibers?
Reticular connective tissue
Reticular connective tissue’s fibroblasts are called
reticular cells
Reticular connective tissue supports free blood cells in ___ ___, the ___, and bone marrow
lymph nodes, spleen,
Connective tissue proper tissue which is closely packed bundles of collagen fibers running parallel to direction of pull
Dense regular connective tissue
Dense regular connective tissues parallel running collagen fibers are ___ structures with ___ ___ to pulling. Fibers are slightly ____ to allow for some stretch.
white, great resistance, wavy
Dense regular connective tissue’s fibroblasts manufacture
fibers and ground substance.
Dense regular connective tissue has ___ cells and is ___ vascularized.
few, poorly
Dense regular connective tissue has parallel ___ fibers and a few ___ fibers.
Collagen, elastic
Dense regular connective tissue’s major cell type is
Fibroblast
Dense irregular connective tissue have the same elements as dense regular connective tissue, but its bundles of collagen are __ and __ __ . Resists tension from many directions
thicker, irregularly arranged
Dense irregular connective tissue has irregularly arranged ___ fibers, some ___ fibers.
collagen, elastic
Elastic connective tissue is __ __ __ tissue containing a high proportion of ___ fibers
dense regular connective, elastic
What are the cells associated with Cartilage?
Chondroblasts, chondrocytes
Cartilage is tough yet flexible, lacks ___ fibers, and is up to __ % water - can rebound after compression.
nerve, 80 %
How does cartilage receive nutrients since it is avacular?
Nutrients from membrane surrounding it - perichondrium
Three types of cartilage are:
Hyaline
Elastic
Fibrocartliage
Hyaline cartilage has an amorphouse but firm matrix, has ___ fibers which form an imperceptible network.
collagen
Chondroblasts produce the matrix and after matured (chondrocytes), lie in ___
lacunae
Elastic cartilage is similar to hyaline cartliage, but has more __ __ in the matrix.
elastic fibers
Fibrocartilage matrix is similar, but less __ than hyaline cartilage.
firm
In fibrocartilage, thick ___ fibers dominate
collagen
What is another name for bone?
Osseous tissue
Bone supports and protects body structures, stores __ and synthesizes __ __ in cavities.
fat, blood cells
True or false: Bone has more collagen than cartilage.
True
What maintains the matrix in bone?
Osteocytes
Bone is __ vascularized.
Richly
What is the most atypical connective tissue?
Blood, a fluid
What is the most common cell type found in blood?
erythrocytes (RBCs)
Blood’s fibers are soluble proteins that ____ during blood clotting
precipitate
Blood’s matrix has __ and __ blood cells in a fluid matrix (__).
Red, white, plasma
Which muscle type is the only one that voluntarily moves?
Skeletal
Which is the only muscle tissue that has multinucleate cells?
Skeletal
Which muscle tissue has intercalated discs?
Cardiac
Which muscle tissues are striated?
Skelatal, cardiac
What controlling tissue regulates and controls body functions?
Nervous tissue
Specialized nerve cells that generate and conduct nerve impulses
Neurons
Supporting cells that support, insulate, and protect neurons
Neuroglia
Which nerve process carry impulses away from the dendrite body?
Axons
Which nerve process carry impulses toward the dendrite body?
Dendrites
Epithelium bound to underlying connective tissue proper
Covering and lining membranes
Covering and lining membranes are composed of at least __ primary tissue types.
Two
What are the 3 types of covering and lining membranes?
Cutaneous membranes
Mucous membranes
Serous membranes
What covering and lining membrane makes up the skin, epidermis, dermis, and is a dry membrane?
Cutaneous membranes
What covering and lining membrane makes up the moist lining in all body cavities that open to the outside of the body?
Mucous membranes, also called mucosae
The term mucosa indicates __ __ __, NOT the cell composition
location of lining
Epithelial sheet lies over layer of connective tissue called __ __.
lamina propria
What covering and lining membrane is found in closed ventral body cavity
Serous membranes
Seroae is __ __ __ (mesothelium) resting on thin areolar connective tissue.
simple squamous epithelium
__ serosae line the internal body cavity walls.
Parietal
__ serosae cover internal organs
Visceral
Pleura line the …?
thoracic wall and lungs
Pericardium lines the …?
Heart
Peritoneum lines the …?
abdominopelvic cavity
Tissue repair occurs in two major ways:
- Regeneration
- Fibrosis
What is regeneration?
- Same kind of tissue replaces destroyed tissue
- Original function restored
What is fibrosis?
- Connective tissue replaces destroyed tissue
- Original function lost
Steps in tissue repair: Step 1 includes
“Imflammation sets the stage”
- Inflammatory chemicals are released
- Dilation of blood vessels
- Increase in vessel permeability
- Clotting occurs
Steps in Tissue Repair: Step 2 includes
“Organization restores blood supply”
- The blood clot is replaced with granulation tissue
- Epithelium begins to regenerate
- Fibroblasts produce collagen fibers to bridge the gap
- Debris is phagocytized
Steps in Tissue Repair: Step 3 includes
“Regeneration and fibrosis”
- The scab detaches
- Fibrous tissue matures; epithelium thickens and begins to resemble adjacent tissue
- Results in a fully regenerated epithelium with underlying scar tissue
Virtually no functional regenerative capacity for:
Cardiac muscle and nervous tissue of brain and spinal cord
Moderate regenerating capacity for:
Smooth muscle and dense regular connective tissue
Regenerates extremely well:
The rest of the tissues and bone found in the body
What are the primary germ layers Superficial to deep?
ectoderm, mesoderm, and endoderm
Ectoderm, mesoderm, and endoderm are formed ___ in embryonic development and specialize to form the 4 primary tissues (nerve, muscle, connective, epithelium)
early
What arises from ectoderm?
Nerve tissue
What arises from mesoderm?
Muscle and connective tisssues
What arises from all three germ layers?
Epithelial tissues