Chapter 4: Cellular Respiration Flashcards
Series of redox reactions; produces ATP- The primary energy currency of cells
Cellular respiration
What is reduction
Gain of an electron (GER)
What is oxidation
Loss of electron (LEO)
True or false: mitochondria is a two membrane system
True
Space inside inner membrane; where citric acid cycle occurs
Matrix
A fold in inner membrane; gives the mitochondria it’s wrinkled shape; provides increased surface area for chemical reactions
Cristae
Between inner and outer membrane; where all the h+ accumulate
Intermembrane space
Two main electron carriers in aerobic cellular respiration
NAD+ (Nicotinamide Adenine Dinucleotide) and FAD (Flavin Adenine Dinucleotide)
How many ATP are created through the process of aerobic cellular respiration from one molecule of glucose?
36 ATP molecules
True or false: ATP is generated through glycolysis
True
Two mechanisms for ATP synthesis
Substrate level phosphorylation and Oxidative phosphorylation
True or false: There are three main stages of aerobic cellular respiration
True
The three main stages of aerobic cellular respiration
Glycolysis, Krebs cycle, electron transport chain
Occurs in cytoplasm; ATP is generated here and this is the link reaction/conversion of pyruvate to acetyl-coa
Glycolysis
This occurs in the mitochondria matrix; citric acid cycle
The Krebs cycle
This occurs in the inner mitochondrial membrane; oxidative phosphorylation
Electron transport chain
Why is pyruvate oxidation necessary?
It acts as the crucial link between glycolysis and the kreb cycle in cellular respiration
Molecule/Central role in cell metabolism and energy production; metabolic intermediate, second messenger, signaling molecule, protein acetylation, fatty acid isoprenoid biosynthesis, and produced in mitochondria from glucose, lipid and amino acid catabolism
Acetyl CoA
A series of 4 protein complexes that couple redox reactions, creating an electrochemical gradient that leads to the creation of ATP and oxidative phosphorylation
Electron transport chain
The FINAL electron acceptor of aerobic cellular respiration
Oxygen
The process where ions move across a semi-perminal membrane down their concentration gradient
Chemiosmosis
The enzyme responsible for Chemiosmosis
ATP synthase
Through the activity of specific enzymes and key stops in the metabolic pathway
How aerobic cellular respiration is regulated
Two forms of fermentation
Ethanol (yeast, wine, beer) and Lactic Acid (muscle/animal cells)
True or false: electrons are transferred from NADH to pyruvate to produce lactic acid (kimchi, pickles, cheese)
True
This uses oxygen to completely break down glucose; producing a large amount of ATP
Aerobic respiration
This occurs without oxygen; breaks down glucose partially and produces significantly less ATP
Anaerobic and Fermentation
If fat’s have more calories per gram, why is glucose a preferred substrate for aerobic cellular respiration?
It can be readily broken down and utilize by the body much faster
Breaks down; hydrolysis; decomposition
Catabolic
Builds up; dehydration; synthesis
Anabolic
True or false: Cells store and retrieve energy by making and breaking chemical bonds in the metabolic reactions
True
Energy required to destabilize existing bonds and initiate a chemical reaction
Activation energy
High energy, unstable state (an intermediate form between substrate and product)
Transition state
True or false: Enzymes function to reduce activation energy
True
Cannot violate laws of thermodynamics
Catalysts (enzymes)
Cannot make an endergonic reaction spontaneous by adding an enzyme
Catalysts
Does not alter the proportion of reactant turned into product
Catalysts
Shape of enzyme stabilizes a temporary association between substrates
Enzymes (proteins)
CO2 + H2O >< H2CO3
Carbonic Anhydrase
Co2 + H2O
Carbon dioxide and water
H2CO3
Carbonic acid
True or false: enzymes particular substrates bind at its active sites
True
When conditions aren’t met, hydrogen bonds break and the enzyme changes shape and stops working
Denaturation
How does an enzyme denature
By unfolding and becoming non-functional
The main purpose of first 3 stages of Cellular Respiration
NAD+ & NADH
True or false: a hydrogen ion (H+) that is neutral, has 1 proton and 1 electron. If that electron is lost what is left is called a proton/hydrogen ion
True
With regard to aerobic cellular respiration, The complete oxidation of glucose proceeds in 4 stages:
Glycolysis, pyruvate oxidation, citric acid cycle, oxidative phosphorylation
Requires oxygen In addition of the phosphate group
Oxidative phosphorylation
Two parts of oxidative phosphorylation
Electron transport chain and chemiosmosis
Functions to create a gradient of protons for hydrogen ions
Electron transport chain
Uses an enzyme called ATP synthase to use that proton gradient to phosphorolize ADP into ATP
Chemiosmosis
Formula for aerobic cellular respiration
C(6)H(12)O(6) (glucose) + (6)O2»_space;» (6)CO2 (carbon dioxide) + (6) H2O (water) + (36) ATP (energy)
True or false: glycolysis starts in the cytosol (outside the powerhouse of the cell/ mitochondria.
True
True or false: glycolysis is a series of 10 different steps or reactions
True
True or false: The end product of glycolysis is pyruvate
True