Chapter 4 Blood and Hemostasis Flashcards
What is blood?
it is a thick fluid made up of cells suspended in a fluid
carried through a closed system of vessels making up the cardiovascular system
Plasma
Liquid portion of the blood that contains clotting factors
Serum
Liquid portion of the blood,m after clotting has occurred and contains NO clotting factors
Anticoagulants
Prevent coagulation or formation of a clot
RBC
Red blood Cell
Erythrocyte
biconcave, disk and have a lifespan of 120 days
no nucelus
Hemoglobin (Hg)
the molecule inside the RBC that carries oxygen
- more oxygen there is a RBC the brighter the red colour
Anemia
decrease in the number and or function of RBC
WBC
luekocytes + colourless
5 different types
“Wright’s stain to differentiate”
6-8 hours in blood stream
5 types of WBC
Neutrophils Basophils Eosinophils Lymphocytes Monocytes
White blood cell count
the test to count the total number of white blood cells present in a given volume
Diff
Differential
is the test to count how many of the different types of WBC are present in a given volume of blood
Leukocytosis
an elevation in leukocytes numbers
Platelets (Plt)
thrombcytes
fragments of bigger cells called megakaryocytes where are found in the blood marrow
lives for 9 days and are constantly being replaced
form a plug when blood vessels are injured
Iron Deficiency Anemia
caused by a lack of iron
Hemolytic Anemia
RBCs are quickly being destroyed in the blood vessels
Aplastic Anemia
all types of blood cells (WBC, RBC and platelets) are decreased; often by drugs
Pernicious anemia
decresad production of RBCs due to a deficiency of vitamin B12
Thalassemia
Abnormal hemoglobin molecules, result in RBCs that cannot carry as much as oxygen (inherbited disorder)
Iatrogenic Anemia
x.x.x.x
Sickle Cell Anemia
one type of thalassemia where the abonormalhemoglobin causes the RBCs to change from a round biconcave shape to a “sickle”
Leukemia
abnormal increase in production of usually one type of WBC
Polycythemia
myeloproliferative disease characterized by an overproduction of RBC by the bone marrow with excess WBC and platelets
Bacteremia
presence of bacteria in the blood which can originate from the respiratory system, urinary tract, abdomen and central venous catheters
Septicemia
results from the presence and persistence of pathogenic bacteria and/or their toxins in the blood
Sepsis
Results from the body responding to severe infection, such as bacteremia
ITP
Idiopathic thrombocytopenic purpura ?????????
Thrombocytopenia
a disorder in which the number of platelests is greatly reduced which results in chronic bleeding through small vessels and capillaries
4 Stages of Hemostasis
- Constriction (or contraction) of the blood vessel
- Formation of a platelet plug
- Formation of a blood clot
- Fibrinolysis (dissolution of the clot)
Hemophilia
a disorder in which the clotting capability of the blood is abnormal or absent
Endocarditis
Heart infrmation