Chapter 4 Flashcards
What are the 4 levels of protein structures?
Primary
Secondary
Tertiary
Quaternary
How are Amino Acids joined?
Covalently through peptide bonds
What do Peptide bonds consist of?
Carboxyl Group and Amino Groups
What does the denature of the protein do and at which level does this occur at?
disrupt structure and function
tertiary
What are the roles of Amino Acids?
Enzymes Storage and Transport Cell shape Decode cell info Horomones Receptors
Protein diversity
Dependent on complexity of organism
How can Freedom of rotation be decreased?
With Double or triple Bonds
The lowest Delta G means what in proteins?
Most stable form
Max number of weak interactions
What are the steps of protein folding?
1) Secondary Structures form
2) Hydrophobic core condenses
3) Tertiary Structure
What do peptide chains have the ability to do?
Add on amino acids duo to it being uncharged
φ
phi, between N amino group and the α-carbon
Ψ
psi, between α-carbon and carbonyl carbon (COO-)
Ramachandran Plot
Tells you allowable combinations of φ and Ψ and how the fold
Primary Structure
linear amino acid sequence,
Secondary Structure
localized interactions within the polypeptide
