Chapter 4

Question 1

what 7 things does the extracellular matrix do

Answer 1

1. forms skeletal elements of tissue 2. modifies morphology and function of cells 3. modulate the survival of cells 4. influence cell development 5. regulates migration of cells 6. direct mitotic activity of cells]7. form junctional associations with cells

Question 2

___ resists forces of compression

Answer 2

ground substance

Question 3

___ withstand tensile (stretching) forces

Answer 3

fibers

Question 4

water is ___

Answer 4

non-compressible

Question 5

ground substance is an ____ material

Answer 5

amorphous gel-like

Question 6

what are the three families of macromolecules that compose the ground substance

Answer 6

glycosaminoglycans, proteoglycans, glycoproteins

Question 7

the three families of macromolecules that compose the ground substance form various interactions with ___, ___, and ___

Answer 7

each other, fibers, cells of CT and epithelium

Question 8

the location of the laminin is almost strictly limited to the ____

Answer 8

basal lamina

Question 9

what are the 3 types of fibers described by histologists based on their morphology and reactivity with histological stains

Answer 9

reticular, collage, elastic

Question 10

____ collagen forms flexible fibers

Answer 10

fibril-forming

Question 11

bundles of collagen fibers are referred to as

Answer 11

white fibers

Question 12

the initial tensile strength of the dermis is attributed to formation of ____

Answer 12

type III collagen

Question 13

the improvement of tensile strength is due to scar maturation when ____

Answer 13

type III collagen is replaced by type I collagen

Question 14

the elevated growth formed by a scar due to excessive accumulation of fiber is referred to as a ___

Answer 14

keloid

Question 15

the synthesis of collagen occurs on the

Answer 15

RER

Question 16

the modified pro collagen molecules are packaged in the ____ golgi network

Answer 16

trans