CHAPTER 4 Flashcards
nucleic acids
polymers specialized for storage, transmission, and use of genetic information (DNA = deoxyribonucleic acid, RNA = ribonucleic acid); grow in the 5’-to-3’ direction
nucleotides
monomers of nucleic acids; made of pentose sugar + nitrogenous base + phosphate group (DNA = deoxyribose, RNA = ribose)
nucleoside
pentose sugar + nitrogenous base
nitrogenous bases
PYRIMIDINES (cytosine, thymine, and uracil) - single ring
PURINES (adenine and guanine) - fused double-ring
phosphodiester bonds
link nucleotides; link the 3’ carbon in one sugar to the 5’ carbon in another sugar
complementary base pairing
purines pair with pyrimidines by hydrogen bonds; can take place between RNA and DNA
RNA
single-stranded, but base pairing can occur between different regions of the molecule with results in 3-D structure, has uracil instead of thymine
DNA
two strands form a double helix; all molecules have the same structure; genetic information is carried in the sequence of base pairs; can reproduce itself (replication); carries hereditary information from one generation to the next
transcription
DNA sequences are copied into RNA (with replication it depends on the base-pairing properties of nucleic acids)
translation
RNA sequences specifies the sequence of amino acids in a polypeptide
transcription + translation =
gene expression
genome
complete set of DNA in an organism
genes
sequences of DNA that are transcribed into RNA
What are the roles for nucleotides?
ATP - energy transfer in biochemical reactions
GTP - energy source in protein synthesis
cAMP - essential in many processes, including hormone action
carriers in synthesis and breakdown of carbohydrates and lipids