chapter 38-39-40-41-42 Flashcards
Which of the following are appropriate tests for neurologic bedside evaluation of a patient with suspected Alzheimer's disease? 1. MMSE 2. Clock drawing test 3. Dementia rating scale 4. Halsteact-Reitan battery
a
Which of the following statements are true regarding mild cognitive impairment?
1. MCI is a normal accompaniment to aging
2. MCI cannot be arrested with current medications
3. All patients with MCI progress to AD
4. Impairment in cognitive performance other than memory predicts decline in patients with
MCI
c
A patient presents for evaluation of memory and is found to have moderate memory loss with
short-term memory mostly affected. The patient has a history of atrial fibrillation and multiple
cerebral infarctions. Imaging shows chronic multifocal ischemic disease. Which is the most likely
diagnosis?
A. Alzheimer’s disease
B. Vascular dementia
C. Cognitive changes with aging
D. Frontotemporal dementia
b
A patient presents for evaluation of memory I0S5 and is found to have global cognitive deficit,
including deficit of short term memory, language, attention, and visual perception. There is a
history of coronary artery disease vvith CABG three-years ago. Neurologic examination is
otherwise normal, including motor and coordination, cranial nerves, reflex. and gait. Which is
the most likely diagnosis?
A. Vascular dementia
B. Alzheimer’s disease
C. Frontotemporal dementia
D. Mixed vascular-degenerative dementia
b
Which of the following clinical presentations is most likely to progress to Alzheimer’s disease?
A. Amnestic MCI
B. MCI with multiple domains impaired
C. MCI with single nonmemory domain affected
a
Which of the following statements are true regarding frontotemporal dementia?
A. Patients can have progressive social and behavioral changes
B. Patients can have progressive fluent aphasia
C. Patients can have progressive nonfiuent aphasia
D. AH are true
d
Which of the following statements is true regarding neuropsychological changes in Parkinson’s
disease?
A. Cognitive deficits develop in 30% of patients with PD
B. Dementia develops in the majority of patients with PD
C. Cognitive deficits are present in the majority of patients with PD
D. Cholinestcrase inhibitors have no effect on the treatment of AD
d
Huntington’s disease is associated with marked cognitive deficits. Which of the following
statements are true regarding HD?
A. The most dramatic early cognitive changes are in executive runcbons
B. Learning and memory deficits are common in HD
C. Memory deficit is equivalent across the periods of ihe patient’s life
D. All are true
d
A 12-year-old girl presents with motor and phonic tics which have a duration and character to
make the diagnosis of Tourette’s syndrome. She has had learning difficulties in school and
neuropsychological evaluation shows attcntional deficit and mood disorders. Which is the most
appropriate clinical impression?
A. The neuropsychological findings cannot be explained by Tourette’s syndrome, and another
etiology for the learning difficulty and tics should be sought
B. The neuropsychologic findings are common and independent of the Tourette’s syndrome
C. The neuropsychologic symptoms and findings are typical of Tourette’s syndrome
D. The neuropsychologic findings are suspect, and repeat evaluation by a second examiner is
needed
c
A 53-year-old man presents with memory loss. He carried the diagnosis of multiple sclerosis on
the basis of previous attacks of optic neuritis and hemiparesis which completely resolved.
Examination shows deficit in short-term memory without othei neurologic abnormality. There
are no signs of aphasia, neglect, or spatial difficulty. MRI shows multiple areas of increased
signal intensity on T2-weighted and FLAIR imaging. None of the lesions enhance with
gadolinium. Which is the most likely diagnosis?
A. Alzheimer’s disease superimposed upon MS
B. Vascular dementia, with ihe original diagnosis of MS being incorrect
C. Vascular dementia, superimposed on the earlier unrelated MS
D Cognitive deimii associated wiih MS
d
A 74-year-old man presents with difficulty with voluntary gaze, but reflex eye movements with
head turning are relatively preserved. What is the most likely cause?
A. Myasthenia gravis
B. Stroke
C. Diabetic mononeuropathy
D. Multiple sclerosis
b
Which of the following are typical of ocular motor apraxia?
A. Inability to perform voluntary saccades
B. Preservation of spontaneous saccades
C. Can be congenital
D. All are true
d
A 76-year-old man presents with diplopia and is found on examination to have absent
adduction of the left eye with right gaze, associated with nystagmus of the right eye. He has a
history of diabetes but not hypertension or hyperlipidemia. Which is the most likely diagnosis?
A. Internuclear ophthalmoplegia due to multiple sclerosis
B. Internuclear ophthalmoplegia due to vascular disease
C. Sixth nerve palsy due to diabetes
D. Mvasthenia gravis
b
An 80-year-old woman presents with right gaze palsy plus the inability to adduct the right eye
with left gaze; there is some associated nystagmus of the left eye Which is the most
he lesion?
A. Cavernous sinus
B. Midbrain
C. Pons
D. Medulla
c
A patient presents with spasmodic ocular deviations, mainiy upward in direction. The eye
movements are eonjugate. Whieii is the most likely diagnosis?
A. Postencephalitic Parkinson’s disease Stroke
B.Stroke
C. Neuroleptics
D. Multiple sclerosis
c
A patient presents with diplopia and is found to have a vertical deviation with one eye slightly
higher than the other. Eye movements are otherwise conjugate with the deviation about the
same with gaze. Wroch is the most likely diagnosis?
A. Ocular mvasthenia
B. Midbrain tumor
C. Fourth nerve palsy
D.Skew deviation due to vascular disease
d