Chapter 35 Flashcards
virus
Any of various submicroscopic agents that infect living organisms, often causing disease, and that consist of a single or double strand of RNA or DNA surrounded by a protein coat. Unable to replicate without a host cell, viruses are typically not considered living organisms.
Virion
the infectious particle that is designed for transmission of the nucleic acid genome among hosts or host cells.
Bacteriophage
a type of virus that attacks only bacteria. It uses the bacteria to reproduce itself. Bacteriophages work by injecting their own DNA into bacterial cells. They use the biological machinery of the bacteria to reproduce, and many more viruses are created this way.
Obligate
Capable of functioning or surviving only in a particular condition or by assuming a particular behavior.
Intracellular parasite
cannot reproduce outside their host cell, meaning that the parasite’s reproduction is entirely reliant on intracellular resources.
Host cell
an animal or plant on or in which a parasite or commensal organism lives.
Epidemic
The occurrence of more cases of a disease than would be expected in a community or region during a given time period.
Pandemic
an epidemic of infectious disease that has spread through human populations across a large region; for instance multiple continents, or even worldwide.
Virulence
refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism - its ability to cause disease - is determined by its virulence factors.
Transmission
the passing of a pathogen causing communicable disease from an infected host individual or group to a particular individual or group, regardless of whether the other individual was previously infected.
Transmission Electron microscopy
Those forms of electron microscopy in which electrons are transmitted through the object to be imaged, suffering energy loss by diffraction and to a small extent by absorption.
Capsid
the protein shell of a virus. It consists of several oligomeric structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The capsid encloses the genetic material of the virus.
Envelope
lipoprotein outer layer of some viruses derived from plasma membrane of the host cell.
Enveloped virus
A virus that has an outer wrapping or envelope. This envelope comes from the infected cell, or host, in a process called “budding off.” During the budding process, newly formed virus particles become “enveloped” or wrapped in an outer coat that is made from a small piece of the cell’s plasma membrane.
acquired immune deficiency syndrome (AIDS)
a human disease characterized by death of immune system cells (helper T cells and macrophages) and subsequent vulnerability to other infections, caused by HIV
Human immunodeficiency virus (HIV)
a retrovirus that causes AIDS in humans
immune system
in vertebrates, the system whose primary function is to defend the body against pathogens. Include cells like helper T cells and macrophages as well as organs like the lymph nodes and thymus
helper T cell lymphocyte/ macrophage
an effector t cell that secretes cytokines and in other ways promotes the activation of lymphocytes. Is descended from an activated CD4+ T cell that has interacted with antigen presented by dendritic cells, macrophages or B cells
Koch’s Postulates
four criteria used used to determine whether a suspected infectious agent causes a particular disease
lytic cycle
a type of viral replication in which a viral genome enters a host cell, new virus particles(virions) are made using host enzymes and eventually burst out of the cell, killing it.
replicative growth
another name for the lytic cycle
lysogenic cycle/ lysogeny
a type of viral replication in which a viral genome enters a host cell, is inserted into the hosts chromosome and is replicated whenever the host cell divides. When activated the viral DNA enters the lytic cycle, leading to the production of new virus particles
nonenveloped virus
virus that consists of genetic material and possibly one or more enzymes inside a capsid (protein coat)