Chapter 3: Cells: The Living Units (pgs. 54-76) Flashcards
cell theory
cell is basic structural and functional unit of living organisms
activity of organism spends on individual and combined activities of cells
principle of complementary structure and function (biochemical activities of cells are dictated by shapes or forms)
cells arise form other cells
generalized or composite cell
contains three main parts
- plasma membrane: outer boundary of the cell that acts as a selectively permeable barrier
- cytoplasm: intracellular fluid containing organelles
- nucleus: organelle that controls cellular activities
extracellular materials
substances contributing to body mass found outside the cell
ex: body/extracellular fluids, cellular secretions, extracellular matrix
body/extracellular fluids
important transport and dissolving media
ex: interstitial fluid, blood plasma, cerebrospinal fluid
interstitial fluid baths organs in amino acids, sugars, fatty acids, regulatory substances and wastes
cellular secretions
substances that aid in digestion and acts as a lubricant
extracellular matrix
most abundant extracellular material
molecules secreted by the cell self assemble into an organized mesh where they help hold cells together
plasma membrane
separates the intracellular fluid from the extracellular fluid
made up of phospholipids, glycolipids and cholesterol
glycolipids
lipids with attached sugar groups
found on outer plasma membrane surface
~5% of membrane lipids
sugar groups make it polar on the outside
cholesterol
~20% of membrane lipid
wedges platelike hydrocarbon rings between phospholipid tails which stabilize the membrane and decrease mobility and fluidity of membrane
integral proteins
firmly inserted into the lipid bilayer
most are transmembrane proteins that span the entire membrane and protrude on both sides
have hydrophobic and hydrophilic regions
involved in transport
channel proteins
transmembrane proteins involved in transport
cluster together to form pores that small, water-soluble molecules or ions can pass through
carrier proteins
bind to a substance and move it across the membrane
peripheral proteins
not embedded in lipid bilayer, attached loosely to integral proteins and can be easily removed without disrupting the membrane
include a network of filaments that help support the membrane from the cytoplasmic side
some are enzymes, motor proteins or link cells together
glycocalyx
glycoproteins and glycolipids that form a sticky carbohydrate rich area on the cell surface
provides highly specific biological markers on different cell types that approaching cells can recognize it by
tight junctions
series of integral proteins of adjacent cells fuse together to form an impermeable junction that encircles the cell
prevent molecules from passing through extracellular space between cells (ex: stomach lining keeps acid inside)
desmosomes
anchoring junctions
mechanical couplings on the sides of adjacent cells that prevent separation
abundant in tissues subjected to mechanical stress (skin or heart muscle)
gap junction
communication junction between adjacent cells
hollow cylinders call connexons composed of transmembrane proteins connect cell membranes
allow ions, simple sugars and small molecules to pass through water filled channels from one cell to the next
present in electrically excitable tissues (heart and smooth muscle) where ion passage from cell to cell to help synchronize electrical activity and contraction
connexons
transmembrane proteins that make up gap junctions that form hollow cylinders
different kinds vary selectivity for gap junction channel
allow ions, simple sugars and small molecules to pass through the water filled channels
diffusion
tendency of molecules or ions to move from an area where they are in high concentration to an area where they are in low concentration (along concentration gradient)
speed of diffusion is related to molecular size and temperature
selectively permeable barrier
allow some substances to pass through while excluding others
plasma membrane is a barrier to free diffusion because of its hydrophobic core
allows lipids, small molecules and molecules assisted by carrier proteins through
simple diffusion
non polar and lipid-soluble substances diffuse directly through the lipid bilayer
es: O2, CO2, fat soluble vitamins
facilitated diffusion
passive transport process where substances that can’t diffuse through the lipid bilayer
substances could either bind to protein carriers in the membrane and be ferried across or move through water-filled protein channels
carrier-mediated facilitated diffusion
transmembrane integral proteins specific for transporting certain polar molecules or classes of molecules (sugars and amino acids) that are too large to pass through membrane channels
alterations in shape of carrier allow it to envelope and release substance so it can pass through the non polar inside of the membrane
moves down its concentration gradient
channel-mediated facilitated diffusion
transmembrane proteins that transport substances like ions or water through aqueous channels across the membrane
ex: leakage channels, gated channels
leakage channels
channel-mediated facilitated diffusion
always open
allow water or ions to move across concentration gradient
grated channels
channel-mediated facilitated diffusion
controlled (opened or closed) by chemical or electrical signals
can be inhibited by certain molecules, show saturation and are specific
substances move across their concentration gradient