Chapter 3

Question 1

Acute Tolerance

Answer 1

tolerance that develops during a single administration.occurs when drug peaks before the blood level peaks, and the drug effect is gone before the drug is eliminated from the body.

Question 2

Cross tolerance

Answer 2

tolerance to one drug diminishes the effect of another drug.

Question 3

Pharmokinetic tolerance

Answer 3

arises in the increase in ability of the body to metabolize the drug, resulting in fewer molecules reaching the site of action. (involves enzyme induction)

Question 4

the expectation mechanism helps explain the ____ effect

Answer 4

placebo

Question 5

placebo induced analgesia utilizes the _____ cortex and _____ gyrus

Answer 5

dorsaolateral prefrontal cortex and the anterior cingulate gyrus

Question 6

Nocebo effect

Answer 6

when the placebo causes side effect association with the actual drug

Question 7

T/F The levels of dopamine in rats proved to actually increase in the nucleus accumbens if the rats were allowed to self administer the drug. Who did this research?

Answer 7

True. Roves and Dorkin did.