Chapter 3 Flashcards
Purpose
-be able to identify independent and dependent variables
-Be able to describe independent and dependent variable
Importance
The independent variable is typically the risk factor that influences the dependent outcome variable
Practical application
we typically manipulate the independent variable to influence the dependent variable
Independent Variable
-what is being manipulated
-influences the dependent variable
-cause (independent variable) and effect (dependent variable)
Depenedent Variable
-not manipulated
-the outcome variable
-is “dependent” on the independent variable
Blind study
subject
Double blind study
subject + investigators (admin treatment)
Triple blind study
subject + investigators + person assessing outcome
Placebo (sham)
Any therapeutic procedure (or a component of any therapeutic procedure) which is given
1. deliberately to have an effect or
2. unknowingly and has an effect on a symptom, syndrome disease or patient but which is objectively without specific activity for the condition being treated
Placebo effect
definced as the changes produced by placebos
Placebo (Paul’s definition)
Intervention that should not matter that has a positive outcome
Hawthorne effect
Individuals modify as aspect of their behaviors because they know they are being observed
Mechanism of action -placebo
Psychological: expectations via “verbal cues as modulators of expectancies”
Nocebo
-negative expectation
-when subject knows that they were randomized into the “control” group
Descriptive Studies
Describes the occurrence of a disease in a population, answers the who, where, when to explain