Chapter 3 Flashcards

1
Q

Estimated # of neurons in the human brain?

A

100 billion

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2
Q

Estimated # of synapses?

A

10-100 trillion

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3
Q

Total electrical power generated in the brain?

A

20-25 wattage

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4
Q

intravenous?

A

into the vein

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5
Q

intramuscular?

A

into the muscle

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6
Q

subcutaneous?

A

underneath the skin

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7
Q

intranasal?

A

applied to the mucous membranes of the nose

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8
Q

sublingual?

A

applied under the tongue

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9
Q

transdermal patch?

A

A device attached to the skin that slowly delivers the drug through skin absorption

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10
Q

biotransformation?

A

The process of changing the molecular structure of a drug into forms that make it
easier for the body to excrete it

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11
Q

metabolite?

A

A by-product resulting from the biotransformation process

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12
Q

elimination half-life?

A

The length of time it takes for a drug to be reduced to 50% of its equilibrium level in the bloodstream

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13
Q

latency period?

A

An interval of time during which the blood levels of a drug are not yet sufficient for a drug effect to be observed

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14
Q

synergism?

A

The property of a drug interaction in which the combination effect of two drugs exceeds the effect of either drug administered alone

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15
Q

How do drugs enter the body?

A

-oral administration (by mouth)
-injection
-inhalation
-absorption through skin/membranes

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16
Q

potentiation?

A

the property of a synergistic drug interaction in which one drug combined with another drug produces an enhanced effect when one of the drugs alone would have had no effect

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17
Q

cross-tolerance?

A

a phenomenon in which the tolerance that results from the chronic use of one drug
induces a tolerance effect with regard to a second drug that has not been used before

18
Q

cross-dependence?

A

a phenomenon in which one drug can be used to reduce the withdrawal symptoms following the discontinuance of another drug

19
Q

what is diazepam?

A

Valium; an anti-anxiety medication

20
Q

central nervous system (CNS)?

A

the portion of the nervous system that has the spinal cord and brain

21
Q

peripheral nervous system (PNS)?

A

the portion of the nervous system that has nerves and nerve fibers that carry info to the CNS and outward to muscles and glands

22
Q

sympathetic branch of the ANS?

A

the portion of the autonomic nervous system
that controls bodily changes that deal w/ stressful or emergency situations

23
Q

parasympathetic branch of the ANS?

A

the portion of the autonomic nervous system that controls the bodily changes that lead to
increased nurturance, rest, and maintenance

24
Q

neuron?

A

the specialized cell in the nervous system
designed to receive and transmit information

25
cerebral cortex?
the portion of the fore brain devoted to a high level of information processing
26
synapse?
the juncture between neurons. It consists of a synaptic knob, the intervening gap, and receptor sites on a receiving neuron
27
neurotransmitter?
a chemical substance that a neuron uses to communicate information at the synapse
28
reuptake?
the process by which a neurotransmitter returns from the receptor site to the synaptic knob
29
acetylcholine?
a neurotransmitter active in the para sympathetic ANS, cerebral cortex, and peripheral somatic nerves
30
norepinephrine?
A neurotransmitter active in the sympathetic ANS and in many regions of the brain
31
dopamine?
a neurotransmitter in the brain whose activity is related to emotionality and motor control
32
serotonin?
a neurotransmitter in the brain whose activity is related to emotionality and sleep patterns
33
GABA?
gamma aminobutyric acid; an inhibitory neurotransmitter in the brain. Antianxiety drugs tend to facilitate the activity level of GABA in the brain
34
glutamate?
an excitatory neurotransmitter in the brain. Glutamate receptors are associated w/ actions of PCP and ketamine and w/ feelings of drug craving
35
endorphins?
a class of chemical substances, produced in the brain and elsewhere in the body, that mimic the effects of morphine and other opioid drugs
36
blood-brain barrier?
a system whereby some substances in the bloodstream are excluded from entering the nervous system
37
endocannabinoids?
Brain produced chemicals that mimic the effects of the active ingredient in marijuana and other cannabis products
38
nucleus accumbens?
A region in the limbic system of the brain considered to be responsible for the rewarding effects of several drugs of abuse
39
placebo?
Latin term translated “I will please.” Any inert substance that produces a psychological or physiological reaction.
40
double-blind?
A procedure in drug research in which neither the individual administering a chemical sub stance nor the individual receiving it knows whether the substance is the drug being evaluated or an active placebo