Chapter 27-37 Flashcards

Neuro

1
Q

Foss JFMS 21
cutaneous truncii in normal cats

A

80% unilateral
98% bilateral

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2
Q

Fastener JFMS 20
cutaneous truncii in abnormal cats

A

65% of cats
spinal pain assoc with reflex being present

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3
Q

Mella JFMS 20
feline spinal disease

A

middle aged purebred - IVDD
older cats - ischemic myelopathy
young cats - fx/luxation

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4
Q

Craciun VCOT 22
Contrast enhanced MRI for IVDE

A

Gandolium can aid in surgical planning and improve confidence of level of location/extent of extradural material

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5
Q

Tam VRU 22
Vertebral OSA on MRI

A

has T2 signal heterogeneity, contrast enhancement, and osteolysis on MRI
Contrast enhancement was typically strong and heterogeneous.

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6
Q

Ros JAVMA 22
central cord syndrome

A

● “central cord syndrome” = clinical presentation where patients show more severe paresis in TL than PL
● 2 locations for central cord syndrome were identified: C1-C5 (90% of the time) and C6-T2 (10%)
● not a negative prognostic

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7
Q

Nakamoto VS 21
myelomalacia with/without extensive hemi

A

Survival rate was higher in the extensive hemilaminectomy and durotomy group (100% survival) than standard hemilaminectomy (65% survival)

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8
Q

Trouble JVIM 21
Brachial plexus injury

A

● evaluated compound muscle action potential (CMAP) for return to function
● CMAP was higher in cases that had clinical improvement (4.3 mV vs 0 mV)
● Threshold CMAP >5 mV prognostic for recovery

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9
Q

Lueck JVIM 22
Trazodone administration

A
  • Seven of 32 (22%) dogs had worse scores on their neurologic examination after receiving trazodone, manifesting as new or progressive PR deficits.
    o 18.7% of the dogs had consciousness levels that changed from bright, alert, responsive to quiet, alert, responsive after trazodone administration.
    o No other changes were observed on neurologic examination.
  • Sedation and anxiety scores were significantly different after trazodone administration compared to before
  • Most dogs did not have changes on neurologic examination after trazodone administration. However, approximately 20% of dogs had new or worsening PR deficits after receiving trazodone. Ideally, trazodone should not be given before neurologic examination in dogs.
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10
Q

Kent JAVMA 19
meningovertebral ligament in dogs

A

● all dogs had a meningovertebral ligament, which formed the ventral boundary of the epidural space and consisted of fibrous bands that attached the ventral dura mater to the dorsal surface of vertebral bodies
● pathologic structures ventral to the spinal cord adopted a bilobed shape

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11
Q

Cameron JVECC 20
dogs/cats in TBI

A

● In dogs, nonsurvivors had higher glucose (150 vs 120 mg/dL)–> not in cats
● Modified glasgow coma score was predictive for survivors (higher = better)

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12
Q

Knight JFMS 19
Feline head trauma

A

● 90% of cases had multiple bones of the skull fractured
● TMJ injury occurred in 60%
● increasing age at presentation and presence of internal upper jaw fractures were risk factors for development of complications
● no risk factors for mortality

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13
Q

Caine JFMS 19
TRI and MRI

A

● negative outcome in TBI cases with peripharyngeal pattern of injury and orbital trauma

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14
Q

Gomes JFMS 22
Discospondilitis in cats

A

● all cats presented with spinal hyperesthesia
● Neuro dysfunction seen in 60%
● positive bacterial urine cultures in 11%
● excellent outcome in 85% with conservative management

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15
Q

Kristiansen VCOT 22
Nucleus pulposus extrusion in dogs

A

● thoracolumbar hydrated nucleus pulposus extrusion was more often painful and extruded disc material was more often lateralized
● TL HNPE were more commonly compressive, more often received surgery
● No difference in outcome between cervical and TL HNPE or conservative vs surgical treatment

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16
Q

Trub JVIM 21
C-reactive protein in disco in dogs

A
  • Serum CRP concentration was significantly more sensitive than were fever and leukocytosis for predicting the presence of diskospondylitis.
  • Serum CRP concentration was more sensitive than neutrophilia and hyperglobulinemia. No difference in serum CRP concentration was found between dogs with single or multiple lesions,
  • nor between dogs with or without empyema, muscular involvement or spinal cord compression.
  • No association was found between serum CRP concentration and positive bacterial culture
  • C-reactive protein is a sensitive, but non-specific biomarker for diskospondylitis which may prove useful as an adjunctive diagnostic test in patients with suspicious clinical signs and may help predict prognosis.
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17
Q

Gomes JVIM 22
CT features in disco in dogs

A
  • The most frequently found changes were: (1) endplate involvement (87.3%) most frequently bilateral (94.5%), with erosion (61.9%) and multifocal osteolysis (67.3%); (2) periosteal proliferation adjacent to the IVDS (73%) and spondylosis (66.7%); and (3) vertebral body involvement (66.7%) involving one-third of the vertebra (85.7%) with multifocal osteolysis (73.5%). Other less prevalent features included an abnormal IVDS (narrowed or collapsed), sclerosis of the adjacent vertebral body or endplates, presence of disseminated idiopathic skeletal hyperostosis or vacuum artifact.
  • We determined that bilateral endplate erosion and periosteal proliferation were very common in dogs with discospondylitis. Careful evaluation of CT in all 3 planes (dorsal, sagittal, transverse) is necessary to identify an affected IVDS. These described CT features can aid in the diagnosis of discospondyli- tis in dogs but equivocal cases might still require MRI.
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18
Q

West JVIM 23
Non traumatic hemorrhaging myelopathy in dogs

A
  • Non-traumatic spinal cord hemorrhage (NTSH) is an uncommon cause of myelopathy in dogs.
  • The onset of signs was acute and progressive in 70% of cases; spinal hyperesthesia was variable (48%).
  • Hemorrhage was identified in the thoracolumbar spinal segments in 65% of dogs. An underlying cause was identified in 65% of cases.
  • Overall, 64% of dogs had a good or excellent outcome, regardless of cause; which was increased to 100% for SRMA, 75% for A. vasorum and 75% for idiopathic NTSH.
  • Outcome was not associated with neurological severity. Recovery rate was 67% and 50% for nociception-intact and nociception-negative dogs, respectively.
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19
Q

Bourbon VRU 23

A
  • Anecdotally, during the review of CT and MRI studies of canine patients including the cranial cervical spine, authors have identified a small osseous structure between the atlas (C1) and axis (C2) with no relevant clinical signs. This structure appeared comparable to a “persistent ossiculum terminale” in humans.
  • Mean age was 85 months (6–166) and breed variation was present.
  • A total of 20 imaging studies were evaluated: CT was performed in 17 dogs; MRI in three dogs; two dogs had both MRI and CT performed. In all cases the presence of at least one small osseous body on the cranial aspect of the odontoid process compatible with a persistent ossiculum terminale was identified as a possible incidental finding without any overt clinical implications.
  • Findings indicated that a small osseous body on the cranial aspect of the odontoid process (presumed persistent ossiculum terminale) in CT and MRI studies may be present in dogs with no clinical signs of neurologic disease.
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20
Q

Planchamp VS 22
CT and MRI cutoff for AA

A

● cutoff values for ventral compression index >0.16 in extended and > 0.2 in flexed positions were diagnostic for atlantoaxial instability with >95% sensitivity

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21
Q

Planchamp VS 22
Head position for AA

A

● all transarticular imaging measurements were dependent on head neck position
● recommended a standardized head neck position of 50 degrees flexion

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22
Q

White VE 19
angles for AA

A

● when flexed lateral radiographs were evaluated with a cutoff value for atlas-to-axis angle >10, evaluation of all breeds revealed a 90% sensitivity and specificity
● recommended 50
flexed lateral views, with AA instability diagnosed if atlas-to-axis angle >10*
● AAA: angle obtained by drawing intersecting lines between roof of C1 and roof of C2

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23
Q

Leblond VCOT 18
trans articular screw vs PMMA AA

A

● Transarticular screw – achieved better apposition than cemented constructs
● Overall, 5% of screws were in dangerous position
● PMMA group were less prone to failure when mechanically tested

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24
Q

Toni JSAP 20
AA stabilization with bicortical screws

A

● stabilized using screws and PMMA
● 93% of screws were placed fully within the pedicle; 7% breached medial pedicle wall
● adverse events in 5/12
● 2/12 died postop; 80% of survivors had improvement in Modified Frankel score

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25
Q

Waschk VCOT 18
anomalies in AA

A

● only dogs with atlantoaxial instability had dens axis anomalies such as separation or abnormal conformation
● patients with AAI were more likely to have other craniovertebral junction abnormalities

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26
Q

Hamilton-Bennet VS 18
3D printed guide for AA

A

● worked well… used to stabilize caudal cervical instability/fracture; screws placed from ventral
● minor vertebral canal breach in 9%

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27
Q

Argent JSAP 22
recurrent with cervical IVDE

A

● 30% success with cervical IVDH treated conservatively
● 70% success with cervical IVDH treated surgically
● recurrence of signs in 34% (⅔ of these cases were initially treated conservatively)
● following surgical cases, recurrence of signs was mostly due to disc extrusion at an IVD site adjacent to initial surgery, not at the same site
● rate of recurrence not different between cases managed conservatively and surgically

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28
Q

Olender JAVMA 23
cervical jerk

A
  • Jerks all presented as focal repetitive rhythmic contractions on the lateral aspect of the neck (on one or both sides).
  • All dogs had a diagnosis of cervical intervertebral disk extrusion (IVDE), half of them at the C2-C3 level. No dogs presented with extrusion caudal to the C4-C5 interverte- bral disk space.
  • Cervical jerk associated with cervical pain or myelopathy may represent myoclonus and was exclusively secondary to cranial cervical IVDE in this study. Full recovery was observed following medical or surgical treatment of IVDE. The exact origin and classification of this involuntary movement has yet to be established.
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29
Q

Murthy JVIM 23
horners syndrome in cervical myelopathy

A
  • Non-compressive disease occurred more frequently in the Horner group compared with controls
    o The most common diseases were fibrocartilaginous embolism in the Horner group and intervertebral disc extrusion amongst controls.
  • On MRI, parenchymal hyperintensity was seen more commonly in the Horner group compared with controls
  • In the Horner group, dogs that did not survive to discharge had more extensive MRI lesions relative to the adjacent vertebral length compared with survivors
  • Lateralization of Horner signs and MRI changes matched in 54% of cases.
  • The overall survival rate was high in both Horner (80/93; 86%) and control (95/99; 96%) groups.
  • Horner syndrome in cervical myelopathy is commonly associated with noncompressive intraparenchymal disease.
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30
Q

Albuquerque Bonelli VRU 21
neurologic signs with MRI

A

● 25% large breed; 75% giant breed
● male predilection
● Dogs with multiple site of compression associated with higher severity of compression and foraminal stenosis
● disc degeneration in 80T of cases
● No age association with severity of compression

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31
Q

Bonelli JAVMA 19
GSD MRI findings with cervical CSM

A

● 90% male
● 90% chronic signs
● osseous proliferation of the articular processes was seen in 60%
● 80% also had ligamentum flavum (yellow ligament) hypertrophy

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32
Q

Reints VS 19
cervical fusion for caudal CSM

A

● Used the SynCage spacer then stabilized using two Unilock plates
● pain and neuro scores improved in all dogs
● implant failure in 45%
● Adjacent site pathology in 78% (not clinical)
● ~80% bone ingrowth seen

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33
Q

Nye JVIM 20
long term follow up with osseous CSM

A

● of sites with stenosis, 45% unchanged, 20% improved, and 40% worsened
● long-term follow did not identify clinical or MRI progression of lesions in the majority of dogs

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34
Q

Albuquerque Bonelli JVIM 23

A

● Forty of the 60 dogs (67%) had concurrent osseous and disc- associated spinal cord compression in the same location.
○ This was considered the main compression site in 32/40 (80%) dogs.
○ Dogs with osseous- and disc-associated compressions at the same site were more likely to have a higher neurologic grade (P = .04).
● A substantial percentage of dogs with CSM present with concomitant IVD protrusion and osseous proliferations, most at the same site. Characterizing this combined form is important in the management of dogs with CSM because it could affect treatment choices.

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35
Q

Mateo VS 20
ventral access to cd cervical/cr thoracic

A

● median manubriotomy improved surgical access to the ventral aspect of caudal cervical and cranial thoracic spine without, can be considered in ventral decompression or stabilization cases

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36
Q

Schmidli VCOT 18
2nd cervical fx

A

● variable severity of neuro signs (cervical pain to tetraparesis)
● 80% had recovery without persistent neuro signs (good recovery seen with both surgical and conservatively managed cases
● low perioperative mortality

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37
Q

Dyall VCOT 18
SSI and hemi

A

● overall SSI rate 0.6%
● no dogs received perioperative ABX

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38
Q

Zidan JVIM 20
long term PO pain from hemi

A

● sensory thresholds at the surgery site normalize by 6 months after surgery
● 15% of dogs with spinal cord damage may develop chronic neuropathic pain

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39
Q

Fenn JVIM 20
anesthesia and IVDE

A

● all dogs had paraplegia with absent pain perception
● confirmed a negative association between increased duration of anesthesia (and surgery) and outcome

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40
Q

Jeffery VS 20
extended durotomy for IVDE

A

● all dogs (24) paraplegic, deep pain-negative
● performed four-vertebral body length durotomy centered on herniated disc
● No detrimental effects of durotomy - “extended durotomy appears safe and may improve outcome of dogs with severe TL contusion and compression
● 67% recovery of neuro status

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41
Q

Takahashi VS 20
durotomy with IVDE

A

● percentage of dogs regaining ambulation was better in the durotomy group (57%) than standard hemilaminectomy group (39%)
● No dogs in durotomy group died of myelomalacia; ~20% of hemilaminectomy dogs died of myelomalacia
● performing durotomy in combination with decompression improved return to function and prevented myelomalacia

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42
Q

Gordon-Evans VS 19
BCS and recovery

A

● increased disability index (i.e. more severe neuro signs) score was associated with increased risk of slow postoperative recovery
● BCS, and age not prognostic
● on average, dogs lost weight and body fat but gained muscle mass with rehab

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43
Q

Mojarradi JSAP 21
hydrotherapy and hemis

A

● “hydrotherapy is unlikely associated with occurrence of postoperative complications”

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44
Q

Woelfel VS 21
extensive epidural hemorrhage

A

● recovery of ambulation in 78% of dogs with pain perception and 40% of dogs without pain perception
○ normally, intact pain with plegia has 90% recovery; loss of pain perception has 60% recovery
● progressive myelomalacia in 5%
● prognostic factors for outcome: loss of pain perception/clinical severity, number of vertebra with signal interruption, and ratio of vertebral sites decompressed to number of vertebrae with signal interruption
● dogs with extensive epidural hemorrhage have a less favorable outcome after surgical decompression than standard IVDE paraplegic dogs
● more extensive decompression improcomes

45
Q

Johnson JVIM 22
hydromelia and IVDE

A

● hydromyelia was identified at sites of IVDE in 84/91 dogs
● absence of hydromyellia was associated with longer duration of clinical signs
● MRI finding of hydromyelia might be a predictor of lesion chronicity
● hydromyelia = distention of central canal
● syringohydromyelia = cavity formation within the spinal accord parenchyma

46
Q

Schueler JSAP 18
lipase and IVDE

A

● serum canine pancreatic lipase was increased in dogs with IVDE

47
Q

Martin JSAP 20
surgery time and IVDE

A

overnight delay before spinal decision increases the risk of clinically meaningful deterioration in dogs unable to walk following TL disc extrusion

48
Q

Upchurch VCOT 20
surgery time and IVDE

A

● duration of clinical signs prior to surgery and rate of onset of signs did not correlate with return of pain sensation, urinary continence, or ambulation
● preoperative neuro grade was main variable that was associated with outcome (shocking)
● delay from clinical signs to surgery is unlikely to affect outcome

49
Q

Dongaonkar VS 21
irrigation

A

● intermittent bolus irrigation was associated with lower peak vertebral canal temperatures than continuous irrigation, but both were effective

50
Q

Tirrito JAVMA 20
surgeon perception

A

● Median spinal cord compression preop 45%, 9% postop
● surgeon’s perception of adequate spinal cord decompression may be less reliable
● Unsatisfactory spinal cord decompression seen with increased severity of preop neurologic grade, preoperative compression, and TL discs

51
Q

Hodshon JAVMA 18
transient pelvic limb reflexes with TL myelopathy

A

● 20% of the time dogs with TL spinal cord lesions can develop transient depression of PL reflexes (may influence neuroanatomic localization)

52
Q

Bravo JSAP 19
lidocaine patch

A

● 5% lidocaine patches did not provide additional postoperative analgesia in dogs undergoing hemilaminectomy

53
Q

Schmierer VS 20
pregabalin

A

● pregabalin reduced pain levels rather than opioids alone

54
Q

Skytte JAVMA 18
neuro score and micturition/ambulation

A

● mean interval from surgery to regain micturition was 4 days
● mean time to regain ambulation was 13 days
● significant negative correlation with severity of signs/modified frankel score for both urination and ambulation

55
Q

Harris VCOT 20
Fenestration leads to new disc material %

A

33

56
Q

Hall VCOT 21
practice of fenestration

A

● fewer surgeons (55%) than neurologists (82%) fenestrated

57
Q

Irizarry VS 22
Percutaneous laser disc ablatino

A

● there were no disc extrusion or spinal cord lesions identified
● lesions were more common in the caudal endplates of the disc space

58
Q

Kerr JSAP 21
IVDE and Frenchies

A

● 51% of frenchies that had decompressive surgery for TL or cervical IVDE had recurrence of signs
● median time between decompressive surgery and recurrence 10 months
● didn’t mention if they recurred at the same or different spaces

59
Q

Longo JVIM 21
recurrence from sx treated IVDE

A

● clinical signs recurred in 36%
● finding a completely degenerate disc in T10-L3 region at the time of initial surgery was associated with hazard ratio of 3 for recurrence of clinical signs

60
Q

Paran JSAP 23
GER in dogs undergoing MRI for TL pathology

A
  • Fifty percent (95% confidence interval: 45 to 57%) of included dogs had evidence of gastroesophageal reflux.
    o Reflux was not associated with the individual breed, age, sex, neuter
    status or body weight.
  • Brachycephalic dogs did not demonstrate significantly higher rates of reflux compared to non-brachycephalic dogs.
    o A larger volume of reflux was associated with a higher chance of regurgitation.
  • Gastroesophageal reflux is a common finding in dogs undergoing thoracolum-
    bar spine magnetic resonance imaging. Dogs which regurgitated had higher volumes of reflux. Early detection and quantification of the volume of reflux is helpful as it may allow the anaesthetist to take measures which may reduce the risk of associated complications.
61
Q

Aikawa JSAP 22
vertebral stabilization for instability in pugs

A
  • Seven dogs were presented with ambulatory or non-ambulatory paraparesis. Caudal articular process anomalies (three dogs) and concomitant cranial and caudal articular process anomalies (four dogs) were noted.
  • Myelography (six dogs) or magnetic resonance imaging (one dog) showed none to severe spinal cord compression.
  • These dynamic compressions were located at sites with articular process anomalies (seven sites) and sites with no articular process anomalies (two sites).
  • Vertebral instability was confirmed by intraopera- tive spinal manipulation in all dogs.
  • Dynamic myelography and/or intraoperative spinal manipulation demonstrated vertebral instabilities at sites with or without articular process anomalies on imaging. Decompressive laminectomy with vertebral stabilisation resulted in long-term neurological improvement in most dogs.
62
Q

Sakaguchi JAVMA 2023
extruded material and near status

A
  • Weak positive correlation was found between the volume of the extruded materials into the vertebral canal and the grade of neurologic severity.
63
Q

Siu JAVMA 23
bacteriuria in dogs following IVDE sx

A

Clinical signs of bacteriuria may be limited to new-onset urinary incontinence, inappropriate urination, or both. Delaying antimicrobial treatment until clinical signs of bacteriuria developed did not result in adverse conse- quences or systemic illness

64
Q

Silva JAVMA 23
Frenchie cervical vs TL region

A
  • The epidural space did not appear to be larger in the cervical than in the thoracolumbar region in this population of French Bulldogs, contrary to previous reports.
65
Q

Bridges JVIM 22
TL disc assoc epidural hemorrhage in dogs

A
  • Sixty-three of 160 (39%) dogs had confirmed EH. French Bulldogs were sig- nificantly overrepresented
  • Dogs with EH were more likely to present with clinical signs less than 48 hours than were dogs without EH and were more likely to be nonambulatory on pre- sentation
  • Dogs with EH were more likely to have <50% cross-sectional spinal cord compression than dogs without EH, longer longitudinal spinal cord compression (3 spaces vs 1 space, P < .001), and greater intrinsic spinal cord change (grade 3/severe vs grade 1/mild; P < .001) based on MRI.
  • The location of the intervertebral disc herniation in French Bulldogs with EH was more likely to be thoracolumbar
66
Q

Lovell JVIM 22
fentanyl or ketamine-dex PO spinal sx

A
  • No difference was found in time to recovery of ambulation between groups or in pain scores. Differences in time to recovery of eating and urination were small but favored ketamine- dexmedetomidine
  • There was no evidence that, at the doses used, fentanyl impaired ambulatory outcome after surgery for thoracolumbar intervertebral disc herniation in dogs. Pain control appeared similar between groups.
67
Q

Wachowiak JVIM 22
TL myelopathy in pugs

A
  • Magnetic resonance imaging revealed 3 dogs with Constrictive myelopathy (CM)only, 17 with CM plus at least 1 other myelopathy, 11 dogs with non-CM myelopathies only, and 1 with no MRI abnormalities.
    o Nineteen of 32 dogs had >1 myelopathy diagnosis on MRI whereas 15/32 had >1 site of spinal cord compression. All dogs had CAPD at >1 site in the T3-L3 vertebral column on CT.
  • Constrictive myelopathy affected more than half of pug dogs presenting with chronic thoracolumbar myelopathies. Most had multilevel disease, concurrent myelopathies, or both. There was no apparent relationship between anatomic locations of CAPD and most severe myelopathy or myelopathy type.
68
Q

Mehra JVIM 23
Omeprazole for IVDE

A
  • Gastrointestinal signs developed in 10/20 (50%) dogs in the omeprazole group and in 7/17 (41%) dogs in the placebo group (P = .59).
    o Diarrhea was common (8/20 omeprazole, 5/17 placebo), hematochezia was rare (1/20 omeprazole, 1/17 placebo); melena was not observed.
    o Clinicopathologic evidence suggestive of bleed- ing was present in 9/20 dogs treated with omeprazole and in 11/17 dogs that received placebo (P = .23).
    o Fecal occult blood positivity was more common in dogs with GI signs (P = .03).
  • Short-term, prophylactic omeprazole treatment did not decrease clinically detectable GI complications in dogs with acute TL-IVDE.
69
Q

Peschard VRU 23
MRI in dogs with ongoing/recurrent neurological symptoms after sx

A
  • Reherniation and reoperation rates of 4.5%–36% are reported in canine patients treated for intervertebral disc herniation (IVDH).
  • Chondrodystrophic breeds, specifically Dachshunds, overrepresented.
  • Mean number of days between surgery and second MRI was 335. use of MRI as a diagnostic modality for spinal imaging following IVDH surgery
  • In 11 cases, spinal cord compression suspected to be clinically significant was found at the surgical site; the extradural compressive material consisted of intervertebral disc material only, or a combination of intervertebral disc material and hematoma or inflammatory changes in 10 cases, and a displaced articu- lar process and fibrous tissue in one case. The latter is a newly described complication of mini-hemilaminectomies.
70
Q

Cordle VRU 23
MRI confirmation of PMM

A
  • Length of T2-weighted hyperintense spinal cord change and HASTE signal loss were significantly associated with clinically evident, however, there were no significant differences between groups when analysis was restricted to dogs not yet showing clinical signs of PMM.
  • The PMM group also had significantly shorter compressive lesions than the control group, suggesting a possible role of more severe focal pressure at the extrusion site. A segment of total loss of contrast enhancement in the venous sinuses and meninges, a feature not previously described, was more common in the PMM group and the difference approached significance
71
Q

Zanoguerra JSAP 23
surgical timing with deep pain negative TL IVDE

A

not associated with rapidity of recovery
duration and neurologic grade at presentation significantly assoc with recovery

72
Q

Crawford VCOT 18
hemilam with either anulectomy or partial discectomy

A

● Hemi + partial discectomy >annulectomy; significantly increased clinical improvement

73
Q

Fowler JFMS 22
Surgical outcomes in cat TL IVDD

A

● 60% presented with L4-S3 lesion
● most common site was L6-7 (33%)
● 90% positive outcome with surgery
● no association was identified between severity of disease and clinical outcome

74
Q

Bibbiani JFMS 22
IVDH in cats

A
  • Most common type of IVDH was ANNPE (n = 22), followed by IVDP (n = 19) and IVDE (n = 9).
    o Cats with a single IVDH were statistically significantly associated with a diagnosis of ANNPE (P = 0.023) compared with cats with multiple IVDHs affected by IVDP (P = 0.004).
  • Neuroanatomical localisation included L4–S3 (n = 19/43), T3–L3 (n = 18/43) and C1–C5 (n = 6/43). Males were more commonly affected by IVDE (P = 0.020) and females by ANNPE (P = 0.020).
  • Cats with IVDP had a longer duration of clinical signs (P <0.001) than cats with ANNPE and demonstrated milder neurological deficits (P = 0.005).
  • IVDEs were statistically significantly associated with spinal hyperaesthesia (P=0.013), while ANNPEs were not (P=0.014).
75
Q

Mathiesen VS 18
ventral stabilization of thoracic kyphosis through intercostal thoracotomies

A

● all dogs undergoing vertebral stabilization using SOP placement experienced a good outcome
● one lung lobe laceration, 2 seromas (6 dogs in study)

76
Q

COnte VCOT 20
thoracic vertebral canal stenosis in brachy

A

● cranial thoracic vertebral canal stenosis is observe most commonly in young, male bulldogs
● stenosis ratio of 0.56 had 67% sensitivity to differentiate between dogs with and without neuro signs

77
Q

Wyatt JAVMA 18
nonsx treatment of thoracic vertebral body malformations

A

● all dogs screw-tail brachy dogs
● all dogs had ambulatory paraparesis and ataxia; all cases progressed
● nonsurgical treatment of congenital thoracic vertebral body malformations was associated with unfavorable outcome

78
Q

Gluding JSAP 21
Genetic background of LS transitional vertebrae in GSD

A

moderate heritability

79
Q

Inness VCOT 21
distraction stabilization for LS dtenosis

A

● technique: dorsal laminectomy, annulectomy, and distraction-stabilization with pins and PMMA
● 95% of cases were due to disc protrusion; 75% had sclerosis of caudal end-plate of L7
● 85% had improved function; 100% improved pain postop
● mean LS step defect reduced 60%, mean foraminal width increased 50%

80
Q

Lichtenhahn Vet Surg 20
Evaluation of L7-S1 nerve root pathology with MR

A

● loss of foraminal fat signal was seen in 75% of cases
● loss of foraminal fat signal associated wtih L7 radiculopathy and foraminal stenosis
● unilateral lesions associated with clinical sings on ipsilateral limb

81
Q

TOni VCOT 20
Accuracy of pedicle screw placement in LS

A

● 30/32 screws were fully within pedicle

82
Q

Zindl VS 18
novel pedicle screw-rod fixation in LS joint

A

● compared to intact , laminectomy resulted in increase in angular displacement at L6-7 and L7-1
● pedicle screw-rod fixation system resulted in a significantly reduced motion at L7-1 with a concomitant increase at adjacent level (L6-7) → ADJACENT SEGMENT SYNDROME/DOMINO EFFECT

83
Q

Saunders VS 18
rostral projection of sacral lamina in LS stenosis

A

● The sacral lamina did not extend as far rostrally in affected dogs, compared to unaffected dogs
● Rostral projection of the sacral lamina, previously proposed as a potential risk factor in dogs with CES due to lumbosacral degeneration, was not associated with a diagnosis of DLSS in this study; the opposite was true.

84
Q

Worth VCOT 18
lateral foraminotomy

A

● 5/6 successful outcome with foraminotomy 🡪 alleviation of pain and increased activity level
● 650-800% increase in volume of the intervertebral foramen following surgery (osseous regrowth at foramen reduced foramen volume ~50%)
● achieved persistent enlargement of foramen 24 months PO, however, osseous regrowth at site may limit effectiveness longer term 🡪 repeat sx may be necessary

85
Q

Garcia VS 21
cats with urine retention after sacrocaudal lux

A

● 100% cats recovered normal micturition spontaneously within 50 days
● long-term cystostomy was effective at managing urinary retention post-sacrocaudal luxation

86
Q

Muniz VS 20
bulldogs with spinal LS

A

● presenting complaint urinary and fecal incontinence in 100%
● dorsal laminectomy in all do for removal of meningeal sac
● postoperative urinary and fecal incontinence improved in 33%, paraparesis improved in ⅔

87
Q

Bresciani VS 21
LS IVDE in dogs

A

● 7/13 neuro signs, all presented for pain with nerve root signature
● MRI revealed lateralized herniated disc material in all cases
● excellent outcome in 85% treated with dorsal laminectomy

88
Q

Franklin JSAP 23
sacro-coccygeal IVDE

A
  • This is the first report of a sacrococcygeal disc extrusion resulting in faecal incontinence, with successful surgical management.
89
Q

Tanoue JAVMA 22
PO outcomes on dorsal lam with transarticular screws, pedicle screws, and PMMA

A
  • In all 21 cases, clinical signs were alleviated, proprioceptive deficits were improved from 3 months after surgery, and no recurrence of clinical signs was observed during the observation period.
  • Minor complications were observed in 6 cases (28.6%), including implant failure in 2 (9.5%), delayed healing of surgical wounds in 2 (9.5%), seroma in 1 (4.8%), and swelling of the affected area in 1 (4.8%).
  • There was no case with major complications.
90
Q

Santifort VRU 22
3D MRI angiography

A
  • Overall, the results of this study show that fast 3D CE-MRA of the lum- bar region in dogs is feasible. However, the smaller arteries responsible for the spinal cord vascular supply were not visualized in this study.
91
Q

McBride JVIM 22
spinal shock injury

A

● background: loss of PL reflexes indicates L4-S3 lesion; however, could also indicate T3-L3 myelopathy with concurrent spinal shock
● odds of spinal shock decreased with increasing weight, increasing duration of clinical signs, decreased pelvic limb tone
● odds of spinal shock increased when paraplegia

92
Q

Schmitt VS 21
CT of proposed implant corridors

A

● vertebral corridors ranged from 3.8-5.2 mm; widest at T1
● Ideal angles: T1 38, T2 32, T3-T9 25*
● dorsal approach for T1-T4 would be challenging due to variability found in these vertebrae
● less variability in vertebrae T5-T9, more amenable to dorsal approach

93
Q

Samer VCOT 21
accuracy of freehand pin placement

A

● mean deviation in angle 8*
● most deviations in position were lateral and caudal

94
Q

Woelfel VS 22
cervical locked facets

A

● all dogs small or toy breed dogs with trauma
● relatively severe clinical signs (tetraparesis, tetraplegia)
● only sites of occurrence were C5-6, and C6-7
● all dogs had unilateral dorsal displacement of the cranial articular process of the caudal vertebra relative to the caudal process of cranial vertebra
● 100% ambulatory
● “locked facet” injury should be differential for small or toy-breed dogs with cervical myelopathy secondary to trauma

95
Q

Lewchalermwong VCOT 18
vertebral screw and Rox fixation

A

● New canine vertebral screw and rod fixation (CVSRF) performed better than screw-PMMA in all tests

96
Q

Segal JSAP 18
LS fx repair with SOP

A

● bilateral twisted SOP can be associated with satisfactory result in treating lumbosacral fracture-luxation

97
Q

Couper JFMS 20
urinary and defecatory fx in cats from sacrocaud lux

A

● 90% regained voluntary urinary function
● higher neuro grade associated with decreased likelihood and longer duration of regaining urinary function
● neurologic grade is most important prognostic factor in cats with sacrocaudal luxation (tail pull injury)

98
Q

Caraty JSAP 18
stabilization for tail avulsion in cats

A

● tail reconstruction performed with 2 nylon sutures
○ drilled hole in dorsal spinous process of sacrum; passed nylon suture around transverse process of caudal vertebra and through drill hole, then tied; repeated on other side
● 50% urinary incontinent at surgery (60% regained continence within 1 month)
● 75% of cats regained tail function and pain sensation postop

99
Q

Elford VS 20
pedicle screw in TL spine in dogs with defects

A

● 5% partial penetration of medial pedicle wall

100
Q

Muller VCOT 22
musculature in dogs with/without AA

A

Dogs with AAI showed a significantly lower dorsal-to-ventral muscle-area ratios (d-v-ratio) at levels 2 and 3, d-C2- ratio at level 2 and ratio of moments at all levels.

101
Q

Amengual-Batle JVIM 20
traumatic skull fx

A

● dogs - more commonly had fracture of cranial vault
● cats - more commonly had fractures of face and base of cranium
● cats = multiple fractures
● cranial vault fractures = more likely to develop neuro signs, more likely to die

102
Q

Farkle JVIM 20
seizures with hydrocephalus

A

● seizure prevalence in dogs and cats with internal hydrocephalus was low (2%)
● seizures were not observed in the 2 year period after surgery
● seizures do not appear to be a complication associated with ventriculoperiitoneal shunt

103
Q

Gillespie JAVMA 19
pred vs sx for hydrocephalus

A

● of the cases treated with prednisone, 50% improved, 50% deteriorated
● of surgical cases, 55% improved

104
Q

Parker JVIM 22
seizure after rostrotentorial surgery

A

● dogs with rostrotentorial brain times had early postop seizures in 13% of cases
● perioperative anticonvulsant not associated with postoperative seizures
● seizures postop = more likely to have neuro complications, less likely to survive

105
Q

Kohler JAVMA 18
risk factors for dogs undergoing brain sx

A

● 13% died and 20% developed major complications within 30 days of surgery
● dogs with abnormal preop neuro exam were more likely to develop complications or die
● suboccipital approach were more likely to die

106
Q

Forward VS 18
PO comps after brain sx

A

● early postoperative neuro deterioration seen in 45% (got worse before getting better)
● postoperative complication in 50%
● 90% survival to discharge
● higher postoperative natremia and prolonged hospitalization were associated with postoperative complications

107
Q

Morton JAVMA 22
complications after brain sx

A

● complications in 50% within 10 days
● most common complications postop were neurologic deficits, seizures, and aspiration pneumonia
● 15% short term mortality rate
● long-term complications in 40% (seizures or neuro deficits)

108
Q

Hyde VS 23
Pituitary masses

A
  • The majority of dogs presented for mentation change (12/15).
  • The mean pituitary to brain ratio (P/B ratio) was 1.05 (0.6–1.4).
  • Eleven dogs were diagnosed with a non- functional pituitary adenoma (NFPA).
  • Perioperative mortality was 33% (5/15). The median survival for all dogs was 232 days (0–1658). When dogs that did not survive to discharge were excluded, the median survival time was 708 days.
  • Seven of 10 dogs that survived the perioperative period received adjunctive therapy