Chapter 27-37 Flashcards
Neuro
Foss JFMS 21
cutaneous truncii in normal cats
80% unilateral
98% bilateral
Fastener JFMS 20
cutaneous truncii in abnormal cats
65% of cats
spinal pain assoc with reflex being present
Mella JFMS 20
feline spinal disease
middle aged purebred - IVDD
older cats - ischemic myelopathy
young cats - fx/luxation
Craciun VCOT 22
Contrast enhanced MRI for IVDE
Gandolium can aid in surgical planning and improve confidence of level of location/extent of extradural material
Tam VRU 22
Vertebral OSA on MRI
has T2 signal heterogeneity, contrast enhancement, and osteolysis on MRI
Contrast enhancement was typically strong and heterogeneous.
Ros JAVMA 22
central cord syndrome
● “central cord syndrome” = clinical presentation where patients show more severe paresis in TL than PL
● 2 locations for central cord syndrome were identified: C1-C5 (90% of the time) and C6-T2 (10%)
● not a negative prognostic
Nakamoto VS 21
myelomalacia with/without extensive hemi
Survival rate was higher in the extensive hemilaminectomy and durotomy group (100% survival) than standard hemilaminectomy (65% survival)
Trouble JVIM 21
Brachial plexus injury
● evaluated compound muscle action potential (CMAP) for return to function
● CMAP was higher in cases that had clinical improvement (4.3 mV vs 0 mV)
● Threshold CMAP >5 mV prognostic for recovery
Lueck JVIM 22
Trazodone administration
- Seven of 32 (22%) dogs had worse scores on their neurologic examination after receiving trazodone, manifesting as new or progressive PR deficits.
o 18.7% of the dogs had consciousness levels that changed from bright, alert, responsive to quiet, alert, responsive after trazodone administration.
o No other changes were observed on neurologic examination. - Sedation and anxiety scores were significantly different after trazodone administration compared to before
- Most dogs did not have changes on neurologic examination after trazodone administration. However, approximately 20% of dogs had new or worsening PR deficits after receiving trazodone. Ideally, trazodone should not be given before neurologic examination in dogs.
Kent JAVMA 19
meningovertebral ligament in dogs
● all dogs had a meningovertebral ligament, which formed the ventral boundary of the epidural space and consisted of fibrous bands that attached the ventral dura mater to the dorsal surface of vertebral bodies
● pathologic structures ventral to the spinal cord adopted a bilobed shape
Cameron JVECC 20
dogs/cats in TBI
● In dogs, nonsurvivors had higher glucose (150 vs 120 mg/dL)–> not in cats
● Modified glasgow coma score was predictive for survivors (higher = better)
Knight JFMS 19
Feline head trauma
● 90% of cases had multiple bones of the skull fractured
● TMJ injury occurred in 60%
● increasing age at presentation and presence of internal upper jaw fractures were risk factors for development of complications
● no risk factors for mortality
Caine JFMS 19
TRI and MRI
● negative outcome in TBI cases with peripharyngeal pattern of injury and orbital trauma
Gomes JFMS 22
Discospondilitis in cats
● all cats presented with spinal hyperesthesia
● Neuro dysfunction seen in 60%
● positive bacterial urine cultures in 11%
● excellent outcome in 85% with conservative management
Kristiansen VCOT 22
Nucleus pulposus extrusion in dogs
● thoracolumbar hydrated nucleus pulposus extrusion was more often painful and extruded disc material was more often lateralized
● TL HNPE were more commonly compressive, more often received surgery
● No difference in outcome between cervical and TL HNPE or conservative vs surgical treatment
Trub JVIM 21
C-reactive protein in disco in dogs
- Serum CRP concentration was significantly more sensitive than were fever and leukocytosis for predicting the presence of diskospondylitis.
- Serum CRP concentration was more sensitive than neutrophilia and hyperglobulinemia. No difference in serum CRP concentration was found between dogs with single or multiple lesions,
- nor between dogs with or without empyema, muscular involvement or spinal cord compression.
- No association was found between serum CRP concentration and positive bacterial culture
- C-reactive protein is a sensitive, but non-specific biomarker for diskospondylitis which may prove useful as an adjunctive diagnostic test in patients with suspicious clinical signs and may help predict prognosis.
Gomes JVIM 22
CT features in disco in dogs
- The most frequently found changes were: (1) endplate involvement (87.3%) most frequently bilateral (94.5%), with erosion (61.9%) and multifocal osteolysis (67.3%); (2) periosteal proliferation adjacent to the IVDS (73%) and spondylosis (66.7%); and (3) vertebral body involvement (66.7%) involving one-third of the vertebra (85.7%) with multifocal osteolysis (73.5%). Other less prevalent features included an abnormal IVDS (narrowed or collapsed), sclerosis of the adjacent vertebral body or endplates, presence of disseminated idiopathic skeletal hyperostosis or vacuum artifact.
- We determined that bilateral endplate erosion and periosteal proliferation were very common in dogs with discospondylitis. Careful evaluation of CT in all 3 planes (dorsal, sagittal, transverse) is necessary to identify an affected IVDS. These described CT features can aid in the diagnosis of discospondyli- tis in dogs but equivocal cases might still require MRI.
West JVIM 23
Non traumatic hemorrhaging myelopathy in dogs
- Non-traumatic spinal cord hemorrhage (NTSH) is an uncommon cause of myelopathy in dogs.
- The onset of signs was acute and progressive in 70% of cases; spinal hyperesthesia was variable (48%).
- Hemorrhage was identified in the thoracolumbar spinal segments in 65% of dogs. An underlying cause was identified in 65% of cases.
- Overall, 64% of dogs had a good or excellent outcome, regardless of cause; which was increased to 100% for SRMA, 75% for A. vasorum and 75% for idiopathic NTSH.
- Outcome was not associated with neurological severity. Recovery rate was 67% and 50% for nociception-intact and nociception-negative dogs, respectively.
Bourbon VRU 23
- Anecdotally, during the review of CT and MRI studies of canine patients including the cranial cervical spine, authors have identified a small osseous structure between the atlas (C1) and axis (C2) with no relevant clinical signs. This structure appeared comparable to a “persistent ossiculum terminale” in humans.
- Mean age was 85 months (6–166) and breed variation was present.
- A total of 20 imaging studies were evaluated: CT was performed in 17 dogs; MRI in three dogs; two dogs had both MRI and CT performed. In all cases the presence of at least one small osseous body on the cranial aspect of the odontoid process compatible with a persistent ossiculum terminale was identified as a possible incidental finding without any overt clinical implications.
- Findings indicated that a small osseous body on the cranial aspect of the odontoid process (presumed persistent ossiculum terminale) in CT and MRI studies may be present in dogs with no clinical signs of neurologic disease.
Planchamp VS 22
CT and MRI cutoff for AA
● cutoff values for ventral compression index >0.16 in extended and > 0.2 in flexed positions were diagnostic for atlantoaxial instability with >95% sensitivity
Planchamp VS 22
Head position for AA
● all transarticular imaging measurements were dependent on head neck position
● recommended a standardized head neck position of 50 degrees flexion
White VE 19
angles for AA
● when flexed lateral radiographs were evaluated with a cutoff value for atlas-to-axis angle >10, evaluation of all breeds revealed a 90% sensitivity and specificity
● recommended 50 flexed lateral views, with AA instability diagnosed if atlas-to-axis angle >10*
● AAA: angle obtained by drawing intersecting lines between roof of C1 and roof of C2
Leblond VCOT 18
trans articular screw vs PMMA AA
● Transarticular screw – achieved better apposition than cemented constructs
● Overall, 5% of screws were in dangerous position
● PMMA group were less prone to failure when mechanically tested
Toni JSAP 20
AA stabilization with bicortical screws
● stabilized using screws and PMMA
● 93% of screws were placed fully within the pedicle; 7% breached medial pedicle wall
● adverse events in 5/12
● 2/12 died postop; 80% of survivors had improvement in Modified Frankel score