Chapter 26 - Angina Flashcards
1
Q
nitroglycerin(Nitro-Bid, Nitro-Dur) – SHORT ACTING
A
Class: Organic Nitrates
- MOA: relaxes smooth muscle in blood vessel walls, potent vasodilator
- Admin: monitor vitals, may take x3 doses (may take 1 pill, every 5 minutes, times 3), do not stand when taking (can make them feel light-headed/dizzy)
- Use: angina
- AE: headache, hypotension, bradycardia, dizziness, syncope
- Contra: with use of erectile dysfunction medications
- -> Cannot take a nitrate from 24-36 hours of taking nitro tablet; both cause hypotension, vasodilation, and hypertension; patients can get SEVERELY hypotensive with combination of both
2
Q
Isordil – LONG ACTING
A
Class: Organic Nitrates
- Doesn’t work for quick, acute attack
- Patch/pill –> must have a nitrate free period
- -> On in morning,, off at night, or vice versa
3
Q
atenolol (Tenormin)
A
Class: Beta Blockers
- MOA: Beta1 selective blocker: decrease workload by decreasing HR, blood pressure and contractility (when heart is slowed down, it works more efficiently)
- Uses: HTN, angina, MI
- AE: bradycardia, depression of AV node, bronchospasm
- -> Bradycardia because sympathetic response blocked; bronchospasm because sympathetic response (bronchodilation) is blocked
- BBW: acute withdrawing of oral drug can exacerbate angina, increase risk ventricular dysrhythmias and MI (must taper)
4
Q
nifedipine (Procardia)
A
Class: Calcium Channel Blockers
- MOA: inhibits the influx of calcium across cell membranes, causing vasodilation of peripheral blood vessels and coronary arteries
- Uses: HTN, stable/unstable/Prinzmetal’s angina, Raunaud’s phenomenon
- AE: hypotension, flushing, headache, dizziness, lower limb edema, reflex tachycardia (happens if patient abruptly stops med must taper off)
