Chapter 23: Drug Class ARB's

Question 1

Actions:

Answer 1

1. Bind to Angiotensin II receptor sites and block the vasoconstrictor from binding to receptor sites in target organs

Question 2

Uses:

Answer 2

1. Alone or in combination with other antihypertensives to reduces BP
2. African Americans may not respond well to therapy with an ARB only

Question 3

CAE’s

Answer 3

1. Dyspepsia
2. Cramps
3. Diarrhea
4. Headache
5. Orthostatic hypotension

Question 4

SAE’s

Answer 4

1. Hyperkalemia, more commonin patients with renal impairment or DM
2. Can cause birth defects

Question 5

Prototype:

Answer 5

1. Losartan
2. Irbesartan
3. Candesartan

Question 6

Patient Education:

Answer 6

1. Should not ever be on ACEI’s and ARB’s at the same time
2. Notify immediately if pregnant
3. Can cause fetal mortality
4. Watch for hypotension