Chapter 23 Flashcards
What is the Mean Arterial Pressure?
Average pressure throughout each cycle of the heart beat
What is Pule Pressure?
Difference between SBP and DBP
What is Hypertension?
Characterized by an elevation of SBP, DBP, or both.
What are two types of Hypertension?
- Primary: cause unknown, 90%
2. Secondary: caused by another disease or medication
What are the Drug Classes used to treat Hypertension?
- Diuretics
- Beta-Adrenergic Blocking Agents
- ACE Inhibitors
- ARB’s
- Direct Renin Inhibitors
- Calcium Channel Blockers
- Aldosterone Receptor Antagonist
- Alpha-1 Adrenergic Blocking Agents
- Central-Acting Alpha-2 Agonists
- Direct Vasodilators
How does a Diuretic work?
Causes:
- Volume depletion
- Sodium excretion
- Vasodilation of peripheral arterioles
- Loop diuretics cause potassium excretion
True or False: Diuretics are the most commonly prescribed anti-hypertensives
True.
How do Beta-Adrenergic Blocking Agents work?
- Inhibits cardiac response to sympathetic nerve stimulation
- Inhibits renin release from kidneys
What is the use for Beta-Adrenergic Blocking Agents?
Can be used in combinationwith other anti-hypertensives
What are the CAE’s of Bet-Adrenergic Blocking Agents?
- Bradycardia
- Peripheral vasocinstriction (purple, mottled skin)
- Heart failure
- Bronchospasm
- Wheezing
- Masks hypoglycemia in diabetic patients
You should hold the Beta-Adrenergic Blocking Agent medication if your patient exhibits what?
- SBP is less than 100
2. Heart rate is less than 60 bpm
If your patient has Bronchospatic disease (COPD, Asthma) they should not receive what type of drug?
Beta-Adrenergic Blocking Agents
How do ACE Inhibitors work?
Inhibits conervion of ACE enzyme
What are the uses of ACE Inhibitors?
- Can be used as single or combination therapy for Stage 1 or 2 hypertension
- Not as effective in African Americans unless combined with diuretic
In African Americans an ACE Inhibitor is not as effective unless given with what?
Diuretic