Chapter 23 Flashcards

1
Q

What is the Mean Arterial Pressure?

A

Average pressure throughout each cycle of the heart beat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Pule Pressure?

A

Difference between SBP and DBP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is Hypertension?

A

Characterized by an elevation of SBP, DBP, or both.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are two types of Hypertension?

A
  1. Primary: cause unknown, 90%

2. Secondary: caused by another disease or medication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the Drug Classes used to treat Hypertension?

A
  1. Diuretics
  2. Beta-Adrenergic Blocking Agents
  3. ACE Inhibitors
  4. ARB’s
  5. Direct Renin Inhibitors
  6. Calcium Channel Blockers
  7. Aldosterone Receptor Antagonist
  8. Alpha-1 Adrenergic Blocking Agents
  9. Central-Acting Alpha-2 Agonists
  10. Direct Vasodilators
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How does a Diuretic work?

A

Causes:

  1. Volume depletion
  2. Sodium excretion
  3. Vasodilation of peripheral arterioles
  4. Loop diuretics cause potassium excretion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

True or False: Diuretics are the most commonly prescribed anti-hypertensives

A

True.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How do Beta-Adrenergic Blocking Agents work?

A
  1. Inhibits cardiac response to sympathetic nerve stimulation
  2. Inhibits renin release from kidneys
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the use for Beta-Adrenergic Blocking Agents?

A

Can be used in combinationwith other anti-hypertensives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the CAE’s of Bet-Adrenergic Blocking Agents?

A
  1. Bradycardia
  2. Peripheral vasocinstriction (purple, mottled skin)
  3. Heart failure
  4. Bronchospasm
  5. Wheezing
  6. Masks hypoglycemia in diabetic patients
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

You should hold the Beta-Adrenergic Blocking Agent medication if your patient exhibits what?

A
  1. SBP is less than 100

2. Heart rate is less than 60 bpm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

If your patient has Bronchospatic disease (COPD, Asthma) they should not receive what type of drug?

A

Beta-Adrenergic Blocking Agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How do ACE Inhibitors work?

A

Inhibits conervion of ACE enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the uses of ACE Inhibitors?

A
  1. Can be used as single or combination therapy for Stage 1 or 2 hypertension
  2. Not as effective in African Americans unless combined with diuretic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In African Americans an ACE Inhibitor is not as effective unless given with what?

A

Diuretic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the CAE’s of ACE Inhibitors?

A
  1. Nausea
  2. Fatigue
  3. Headache
  4. Diarrhea
  5. Orthostatic Hypotension
  6. 1/3 get a cough
17
Q

SAE’s of ACE Inhibitors

A
  1. Angioedema
  2. Neutropenia
  3. Hyperkalemia
  4. Nephrotoxicity
  5. May cause fetal harm
  6. May increase blood level of digoxin and lithium
18
Q

Prototypes of ACE Inhibitors

A
  1. Lisinopril
  2. Captopril
  3. Enalpril
19
Q

Patient education for ACE Inhibitors

A
  1. Don’t use if history of angioedema
  2. Have them notify prescriber immediately if pregnant or breastfeeding
  3. Less effective with AA
  4. Can cause coughing and hypotension