Chapter 23 Flashcards
Circulates blood through the body’s tissues
Cardiovascular system
Includes the heard, associated arteries, veins, and capillaries (delivers substances to and removes substances from the cells)
the Cardiovascular system
What happens when plasma leaves blood capillaries?
It becomes interstitial fluid
Transport interstitial fluid to lymph vessels and lymph nodes
Lymph capillaries
Contains fixed macrophages, B cells, and T cells
Lymph nodes
What are buboes?
Swollen lymph nodes
An acute illness due to the presence of pathogens or their toxins in the blood
Septicemia
Systemic inflammatory response syndrome (SIRS)
Sepsis
Inflamed lymph vessels
Lymphangitis
Decreased blood pressure and dysfunction of at least one organ
Severe sepsis
Sepsis and uncontrollable decreased blood pressure
Septic shock
What is another name for Gram (-) sepsis?
Endotoxin shock
Cause a severe drop in Blood Pressure
Endotoxins
What bacteria are most frequently involved in endotoxin shock?
Klebsiella spp., E. coli, and Pseudomonas aeruginosa
Treatment for Gram (-) sepsis
Neutralizing the LPS components and inflammatory-causing cytokines
What is Gram (+) sepsis?
potent exotoxins that cause toxic shock syndrome
What are some examples of hospital acquired infections?
Enterococcus faecium, Enterococcus faecalis, Group B streptococci
Also known as puerperal fever and childbirth fever
Puerperal Sepsis
What bacteria causes puerperal sepsis?
Streptococcus pyogenes
Pathogen of streptococcus progenies
transmitted via childbirth; infects the uterus and progresses to an infection of the abdominal cavity
Inflammation of the endocardium
Endocarditis
Impairs the function of the heart valves
Subacute bacterial endocarditis
What bacteria causes Acute bacterial endocarditis?
Staphylococcus aureus
Inflammation of the cat around the heart
Pericarditis
An autoimmune complication of S. pyogenes infections
Rheumatic Fever
What does Sydenham’s chorea cause?
Purposeless, involuntary movements
What bacteria causes Anthrax?
Bacillus anthracis
Is a Gram (+), endospore-forming aerobic rod
Bacillus anthracis
How is Anthrax treated?
With ciprofloxacin or doxycycline
Is found in soil and primarily affects grazing animals
Anthrax
Pathogen of Anthrax
spores are taken in by macrophages and germinate
bacteria enter the bloodstream and release toxins
Disease who’s bacteria produce virulence factors
Anthrax
Binds the toxins to target cells, permitting entry (virulence factor)
Protective antigen
Causes local swelling and interferes with phagocytosis (virulence factor)
Edema toxin
Targets and kills macrophages (virulence factor)
Lethal toxin
Endospores enter through a minor cut, 20% mortality rate without treatment
Cutaneous anthrax
Ingestion of undercooked, contaminated food, >50% mortality rate
Gastrointestinal anthrax
Inhalation of endospores, progresses into septic shock, nearly 100% mortality rate
Inhalation (pulmonary) anthrax
Loss of blood supply to tissue
Ischemia