Chapter 21 Flashcards
What part of the nervous system do cholinergic drugs target
Parasympathetic
What do cholinergic drugs do to the parasympathetic nervous system
Turn it on making the body calm and relaxed. Rest and digest
What is another name for cholinergic agonists
Parasympathomimetics
What are the 2 types of cholinergic receptors
Nicotinic
Muscarinic
Where are nicotinic receptors located
Ganglia
Where are muscarinic receptors located
Postsynaptically in organs
Smooth muscle
Cardiac muscle
Glands
Where does muscarine come from
Mushrooms
Muscarinic and nictoninic. Which is pre and which is post
Pre is nicotinic
Post is muscarinic
How do cholinergic drugs work
Bind to cholinergic receptors
How do indirect acting cholinergic agonists work
Inhibit acetylcholinesterase from breaking down AcH
What parts of the body do cholinergic drugs affect
GI: secretions, motility
Bladder: urination
Eyes: pupils constrict
Sweating and salivation
What do cholinergic drugs do the heart
Decrease HR
Vasodilation
What do cholinergic drugs do to the respiratory system
Bronchial constriction
Narrow airways
Why should patients with asthma use caution with cholinergic drugs
Cause bronchial constriction
What are signs that the dose of the cholinergic is too high and a cholinergic crisis is occurring
Flushed skin
Orthostatic BP
Abdominal cramps and nausea
