Chapter 2 - Abbreviations

Question 1

HPLC

Answer 1

high-performance liquid chromatography

Question 2

UHPLC

Answer 2

ultra-high-pressure liquid chromatography

Question 3

t_R

Answer 3

retention time

Question 4

t_M

Answer 4

void time

Question 5

h

Answer 5

peak height

Question 6

w_b

Answer 6

peak width measured at the base

Question 7

w_½

Answer 7

peak width measured at the peak’s half height

Question 8

N

Answer 8

number of theoretical plates (efficiency)

Question 9

V_R

Answer 9

retention volume

Question 10

V_M

Answer 10

void volume

Question 11

F

Answer 11

flow rate

Question 12

V_c

Answer 12

volume of empty column

Question 13

V₀

Answer 13

intraparticular volume

Question 14

V_e

Answer 14

interstitial volume

Question 15

k

Answer 15

retention factor

Question 16

t_R^’

Answer 16

the time the solute resides in the stationary phase

Question 17

K

Answer 17

partition coefficient

Question 18

V_s

Answer 18

volume of the stationary phase

Question 19

V_m

Answer 19

volume of the mobile phase

Question 20

𝛼

Answer 20

separation factor

Question 21

HETP

Answer 21

height equivalent to a theoretical plate

Question 22

H

Answer 22

plate height

Question 23

d_p

Answer 23

diameter of the particles used as the packing material

Question 24

R_s

Answer 24

resolution

Question 25

A_s

Answer 25

asymmetry factor

Question 26

T_f

Answer 26

tailing factor

Question 27

E^o

Answer 27

Hildebrand’s elution strength scale

Question 28

V

Answer 28

linear flow velocity

Question 29

D_m

Answer 29

diffusion coefficient

Question 30

H_min

Answer 30

minimum plate height

Question 31

V_opt

Answer 31

optimum flow velocity

Question 32

A

Answer 32

multi-path effect

Question 33

B

Answer 33

longitudinal or passive diffusion

Question 34

C

Answer 34

resistance to mass transfer

Question 35

n

Answer 35

peak capacity

Question 36

t_G

Answer 36

gradient time

Question 37

k^*

Answer 37

average k under gradient conditions

Question 38

ΔΦ

Answer 38

change in volume fraction of strong solvent in RPC

Question 39

HTS

Answer 39

high-throughput screening

Question 40

API

Answer 40

active pharmaceutical ingredient peak