Chapter 19 Flashcards
Blood makes up _% of bodyweight
8
Where are each of the following produced: EPO, TPO
EPO: kidneys
TPO: liver
Which agranular leukocyte is deried from the myeloid stem cell lineage?
monocytes
The main stimulus for erythropoiesis is ___. It occurs in the ____.
hypoxia; kidneys
Lymphoid stem cells will differentite into…
agranular leukocytes (except monocytes): T + B cells, NK cells
When does a pro-erythroblast become a reticulocyte?
when the nucleus is ejected
The most abundant WBC in the blood is… which are associated with ______.
neutrophils
bacterial infections, burns, stress, inflammation
What are each of the following associated with?
Basophils, eosinophils, monocytes
Basophils: allergic reactions
Eosinophils: allergic reactions, parasitic infections + AI disease
Monocytes: viral + fungal infections
What are the 3 steps of hemostasis?
- vascular spasm
- platelet plug formation
- coagulation
What are the two steps in getting rid of a blood clot?
- contraction (tightening of fibrin)
2. clot dissolution (fibrinolysis)
What does the enzyme plasmin do?
digests fibrin net in fibrinolysis
What is the role of thrombin?
converts fibrinogen into insoluble fibrin during blood clotting cascade
Thromboplastin is released by…
damaged tissue
T/F: the heart is the first functional organ that develops in the embryo
True
What layer of the heart is made up of connective tissue and mesothelium?
epicardium