22 - Immunity Flashcards

1
Q

Two functions of the lymphatic system:

A
  1. draining interstitial fluid

2. providing mechanism for defence against disease

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2
Q

What are some tissues that make up the lymphatic system?

A

lymph vessels
lymph (fluid)
reticular connective tissue containing a large # of lymphocytes (T, B, and NK cells)
red bone marrow

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3
Q

What are Peyer’s patches?

A

groups of lymphoid follicles in the mucus membrane lining your small intestine

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4
Q

Lacteals run down the centre of a villus (fingerlike projection) and are found in the….

A

small intestine

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5
Q

Lymphatic vessels do/don’t have valves

A

Do

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6
Q

What are the 6 lymph trunks, from inferior to superior?

A
Lumbar
Intestinal
Cisterna chyli (dilated sac at lower end of thoraic duct)
Broncho-mediastinal
Subclavian
Jugular
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7
Q

What is the cisterna chyli?

A

A dilated sac at the lower end of the thoracic duct, where the intestinal trunk and two lumbar trunks join the thoracic duct

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8
Q

The thoracic duct begins at the _____ which is found anterior to ___.

A

begins in the cisterna chyli, anterior to L2

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9
Q

Primary lymphatic organs/tissues (where lymph cells mature) include the…

A

red bone marrow & thymus

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10
Q

Secondary lymphatic organs/tissues (where immune responses occur) include the…

A

lymph nodes/glands (incapsulated)
spleen
lymphatic nodules (lymphoid tissue without a defined capsule)

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11
Q

Differentiate lymphatic organ vs. tissue

A

organ: covered by a capsule
tissue: no capsule

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12
Q

What 4 types of cells are found in the CORTEX of the thymus gland?

A

immature T cells (only 2% survive)
dendritic cells (help T cells mature)
epithelial cells (produce thymic hormones)
macrophages

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13
Q

Hassall’s corpuscles are the site of ____ in the ____ of the thymus gland.

A

site for T cell death in the medulla of the thymus gland

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14
Q

The largest groups of lymph nodes are found in the…

A

breast, axillae, and groin

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15
Q

The largest single mass of lymphatic tissue in the body is the _____, although it does NOT filter lymph.

A

spleen

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16
Q

Where is the spleen found?

A

behind the stomach at the left colic flexure

17
Q

The white pulp of the spleen contains ____ while the red pulp contains _____.

A

white pulp: B & T cells, macrophages

red pulp: removed dead RBCs and platelets (stored 1/3 of platelets) + hemopoiesis in fetal life

18
Q

What are MALTs? Give three examples.

A

mucosa-associated lymphatic tissues (found in mucuous membranes)
tonsils, Peyer’s patches, the appendix