Chapter 18/19 (Pt. 4) Flashcards
how are most nutrients reabsorbed from the proximal tubule?
secondary active transport
what’s the difference between primary and secondary active transport?
primary: uses ATP directly
secondary: uses electrochemical gradient from primary transport
in the active reabsorption of glucose, where do we see primary active transport?
Na/K pump into the cell on basolateral membrane
in the active reabsorption of glucose, where do we see secondary active transport?
Na+ and glucose brought in from lumen into the cell on apical side
in the active reabsorption of glucose, facilitated diffusion?
glucose transporter from inside the cell outside the cell, on the basolateral membrane
in the active reabsorption of glucose, simple diffusion?
glucose diffusing into a peritubular capillary
how are AAs reabsorbed
secondary active transport
how are ions reabsorbed?
passively; and by symporters and exchangers
how is water reabsorbed from the proximal tubule?
osmotic pressure; through aquaporins
secondary active transport
how are most nutrients reabsorbed from the proximal tubule?
primary: uses ATP directly
secondary: uses electrochemical gradient from primary transport
what’s the difference between primary and secondary active transport?
Na/K pump into the cell on basolateral membrane
in the active reabsorption of glucose, where do we see primary active transport?
Na+ and glucose brought in from lumen into the cell on apical side
in the active reabsorption of glucose, where do we see secondary active transport?
glucose transporter from inside the cell outside the cell, on the basolateral membrane
in the active reabsorption of glucose, facilitated diffusion?
glucose diffusing into a peritubular capillary
in the active reabsorption of glucose, simple diffusion?
secondary active transport
how are AAs reabsorbed
passively; and by symporters and exchangers
how are ions reabsorbed?
osmotic pressure; through aquaporins
how is water reabsorbed from the proximal tubule?
AAs are almost completely reabsorbed from the glomerular filtrate via active transport in the ?
proximal tubule
what is the graph telling you about glucose reabsorption and why is 200 mg/dL considered overt diabetes?
at 200 mg/dL, the rate of filtration outstrips that of reabsorption. in other words…
kidney can’t recapture all the glucose back from blood/glomerulus due to a finite number of glucose transporters, so it ends up in the urine.
where does continuous reabsorption occur in the nephron tubule?
proximal tubule
where does regulated reabsorption occur in the nephron tubule?
distal tubule
where does continuous vs. regulated reabsorption occur in the nephron tubule?
proximal: unregulated
distal: regulated
distal tubule: un/regulated reabsorption
regulated
