Chapter 18 Flashcards
variation
differences between individuals of the same species
Continuous variation
Occurs as a range of phenotypes between two extremes, e.g. height in humans. Caused by both genetics and environmental factors.
Discontinuous variation
Occurs in a limited number of phenotypes with no intermediates, e.g. tongue rolling. Mainly caused by genes alone.
mutation
genetic change; the way in which new alleles are formed
Effect of ionising radiation and some chemicals on the body
Increase the rate of mutation (causes cancer lol)
Phenotypic variation
the variation in the features we can see, even with specialised equipment. It is effected by both genetics and environmental factors.
Genetic variation
the variation between the genotypes of different individuals.
gene mutation
a change in the base sequence of DNA
Describe the symptoms of sickle cell anaemia
Sickle shaped red blood cells means less oxygen can be carried and they can cause difficulty breathing, tiredness, crises, delayed puberty, blockage of blood vessels and if the spleen destroys the sickle cells at a greater rate than r.b.c, causes anaemia
Explain how a change in the base sequence of the gene for haemoglobin results in abnormal haemoglobin and sickle-shaped red blood cells
Sickle cell anaemia is caused by a single base substitution in the haemoglobin gene, Hb. A single A base is substituted by a T base. The normal allele Hb A becomes the sickle cell allele Hb S . The change causes haemoglobin to contain valine instead of glutamic acid, causing sickle cells to be produced.
individuals with the sickle cell trait and their relationship with malaria
Due to the sickle cells having an abnormal shape, the parasite that is responsible for malaria can not enter the red blood cells. Therefore they are resistant to malaria.
How the sickle cell allele is a selective agent
People who do not have the sickle cell trait die from malaria, the people who are homozygous with the sickle cell allele die young due to their condition and, as it is codominant, heterozygous individuals don’t suffer from sickle cell anaemia and are resistant to malaria. Therefore more likely to reproduce offspring with the same traits.
Malaria distribution and the sickle cell allele distribution
majority of malaria is found in central Africa, where the sickle cell allele is also very prominent.
adaptive feature
an inherited feature that helps an organism to survive and reproduce in its environment. (or in fancy terms, the inherited functional features of an organism that increase its fitness)
fitness
the probability of an organism surviving and reproducing in the environment in which it is found