Chapter 17-Part 2 Introduction to Bioinformatics Flashcards
What is the goal of the genomic research
Determining Nucleotide Sequence
Genomic Map
Shows the approximate location of gene
Whole genome sequencing
is simply the sequencing of the entire
genome of an organism at one time.
Whole-genome shotgun sequencing
Small-insert clones are prepared
directly from genomic DNA and
sequenced in a highly automated
way.
What is a contig
a set of overlapping fragments that form a continuous
stretch of DNA
What are SNP?
A site in the genome where
individual members of a
species differ in a single
base pair
Haplotype
the specific set
of SNPs and other genetic
variants observed on a
chromosome
Orthologs
Homologous genes in different species that evolved from the
same gene in a common ancestor
Paralogs
Homologous genes arising by duplication of a single gene in the
same organism
Homologous
Genes that are evolutionarily related
Functional genomics
Characterizes what the sequences do
Transcriptome
All the RNA molecules transcribed from a genome
Proteome
Analyzes the complete set of
proteins found in a cell