Chapter 17: Fatty Acid Catabolism Flashcards
About ____ of our energy needs comes from dietary triacylglycerols
1/3
About 80% of energy needs of mammalian heart and liver are met by _______ of fatty acids
Oxidation
Describe fats energy storage
Fats carry more energy, less water
Describe glycogen energy storage
Long term, slow vs short term, fast delivery
During digestion, lipids are transported in the blood as _______
chylomicrons
Why do lipids need to packed in particles for transport?
Lipids are not soluble
What trigger mobilization of stored triacylglycerols?
Hormones
_____ catalyze fat hydrolysis
Lipases
Where does hydrolysis (breakdown of triacylglycerol) happen?
In the cytoplasm of adipocytes
Glycerol from fats enters ______
Glycolysis
The Beta-oxidation of fatty acids occurs in __________
Mitochondria
What are the stages of Fatty Acid Oxidation?
Stage 1: Oxidative conversion of two-carbon units into acetyl-CoA vis beta-oxidation with concomitant generation of NADH and FADH2
Stage 2: Oxidation of acetyl-CoA into CO2 via citric acid cycle with concomitant generation NADH and FADH2
Stage 3: Genertaes ATP from NADH and FADH2 via the respiratory chain
Shorter chains areb prpocessed by _____________ in the matrix
soluble enzymes
Shorter chains (>12) are processed by _____________ in the matrix
soluble enzymes
_____ processes fatty acids chains with 12 or more carbons
TFP