Chapter 17 - Adaptive Immunity Flashcards
________ are human defenses that develop late to handle a particular microbe. _______ can be acquired through infection or immunization.
Adaptive Immunity
________ have specific recognition and response to a specific microbe. ________ also has immunological memory and has a slower immune response than Innate Immunity.
Adaptive Immunity
_______ is the study of host defenses against foreign substances (antigens).
Immunology
_______ is a substance that stimulates a certain immune response through antibody production. Examples of ______ are pathogens, foreign substances, and vaccines.
Antigen (Ag)
________ are protective proteins made by the host in response to certain antigens. _______ are also known as immunoglobulins (Ig).
Antibody (Ab)
________ attacks antigens that have entered the cell (intracellular Ag’s, animal virus present inside host cell)
Cell-Mediated Immunity
________ fight invaders and threats outside of the cell (extracellular Ag’s and toxins)
Humoral Immunity
______involves B cells which “indirectly” make antibodies that help destroy antigens
Humoral Immunity
__________ produces T cells that recognize parts of antigens that get processed by phagocytes & will destroy the antigen.
Cell-Mediated Immunity
_______ are external components that antibodies bind to at the surface of antigens
Antigenic Determinants
________ binds to antigenic determinate and is found at the ends of the arms.
Variable Region
_______ is the stem of the antibody.
Constant Region
_________ is a monomer, the most abundant Ig in the blood, lives for several weeks, and can be found in the blood, lymph, and intestine.
IgG
_______ crosses the placenta (transplacental passage), enhances phagocytosis, and neutralizes toxins and viruses
IgG
_______ is a pentamer, the largest antibody, and remains in blood vessels.
IgM
_______ causes clumping (agglutination) of microbes and is the primary response to an infection.
IgM
________ is mostly a dimer in secretions, the most abundant in the body is common on mucous membrane surfaces and in secretions.
IgA
_________ prevents microbial attachment of pathogens to mucous membranes.
IgA