Chapter 14 - Principles of Disease and Epidemiology Flashcards
_______ is the study of the cause of a disease.
Etiology
_______ is the development of disease.
Pathogenesis
_______ is the study of disease.
Pathology
________ is an abnormal state/condition in which the body is not performing normal functions.
Disease
_______ is the invasion or colonization of the body by pathogens.
Infection
________ are microbes that are always present in/on the human host.
Normal Microbiota
________ is a disease caused by a pathogen.
Infectious Disease
______ is the relationship microbe and the host.
Symbiosis
_______ is the relationship where both organisms benefit.
Mutualism
__________ is a disease not caused by a pathogen.
Non-infectious disease
_____ are microbes that take up temporary residence and remain in the body for only hours to months.
Transient Microbiota
_______ is the relationship when one organism benefits while the other is unaffected.
Commensalism
______ is the relationship where one organism benefits at the expense of the other.
Parasitism
_______ are used to determine the cause of an infectious disease, specific pathogen -> specific
disease.
Koch’s Postulates
______ are changes in body function that are felt by a patient. These changes are not observable nor are they measurable, such as pain and fatigue.
Symptoms
______ are changes in the body that can be measured or observed, such as weight, temperature, and blood pressure.
Signs
______ is a disease that is spread from one host to another. An example of _______ is Chickenpox.
Communicable Disease
_______ is a specific group of signs and symptoms that accompany a disease.
Syndrome
______ is a type of communicable disease that is easily and rapidly spread.
Contagious Disease
________ is a disease that does not spread from one host to another. An example of _______ is tetanus and diabetes.
Noncommunicable Disease
_______ is the number of people who develop a disease during a specific time period.
Incidence
_______ is the number of people who develop a disease at a certain time regardless of when it first appeared and takes into account both old and new cases
Prevalence
________ is a disease that occurs only occasionally, random manner, and with no pattern of disease. Ex: Mad Cow Disease
Sporadic Disease
______ is a disease that is consistently present in a population. Ex: Malaria
Endemic Disease
_______ is a disease acquired by many people in a given area in a short time that spreads quickly. Ex: Influenza
Epidemic Disease (Outbreak)
_______ is a worldwide/global epidemic. Ex: Covid-19
Pandemic Disease
_______ has symptoms that develop rapidly but the disease lasts only a short time.
Acute Disease
_______ has symptoms develop slowly and last a long time.
Chronic/Persistent disease
________ are intermediate between acute and chronic.
Subacute disease
________ occurs when a causative agent is inactive for a time, but then activates and produces symptoms.
Latent Disease
______ is immunity where an entire population is protected and is accomplished through vaccination. This occurs because if most of the population is immunized, then they are less likely to get sick and infect non-immunized people.
Herd Immunity
______ occurs when pathogens are limited to a small area of the body. Ex: Skin Infection
Local Infection
_________ occurs when an infection is spread throughout the body.
Systemic (generalized) Infection
_______ is the uncontrollable spread of a pathogen in the blood and is a life-threatening condition.
Sepsis/Septicemia
_____ occurs when bacteria are in the blood.
Bacteremia
________ occurs when toxins are in the blood
Toxemia
________ occurs when viruses are in the blood
Viremia
______ are acute infection that causes the initial illness. Ex: HIV/AIDS
Primary Infection
______ are caused by opportunistic pathogens after a [primary infection. Ex: AIDS-related opportunistic infections.
Secondary Infection
Gender, Age, Lifestyle, Inherited traits, Climate, Weather, and poor sanitary conditions are all known as ________.
Predisposing Factors
_______ has no signs and symptoms present. This is the interval between the initial infection and the first signs and symptoms.
Incubation
_______ has early, mild symptoms and is after incubation. This is the first appearance of signs and symptoms.
Prodromal Period
_______ has the most severe signs and symptoms.
Period of Illness
_____ leads to either a period of decline or death. ______ also is the stage where Ab titer is the highest.
Peak of Illness
_______ are where signs and symptoms subside.
Period of Decline
_______ is when the body returns to its pre-diseased state.
Period of Convalescence/Recovery
________ are the continual sources of infection. (where is the pathogen found? )
Reservoir
Sick people or “carriers” with no signs and symptoms are known as ________.
Human Reservoir
The source of infection that comes from creatures is known as _______.
Animal Reservoirs
Contaminated inanimate objects such as soil, air, water, and food are known as ________.
Non-living reservoirs
_______ requires a close association (touching) between the infected person and the susceptible host.
Direct Contact Transmission
______ spreads to the host by a contaminated non-living object called a fomite (ex: contaminated doorknob, utensils, etc.)
Indirect Contact Transmission
________ is the transmission via airborne droplets less than 1 meter
Droplet Transmission
______ is transmitted by a contaminated inanimate reservoir.
Vehicle Transmission
_______ transmission via airborne droplets more than 1 meter.
Vehicle Transmission airborne
_______ is accomplished by arthropods, such as fleas, ticks, and mosquitoes, where pathogens can be in or on them.
Vector Transmission
_______ occurs when an arthropod vector carries a pathogen on the outside of its body. This is known as the “passive transport” of pathogens.
Mechanical Vector Transmission
________ occurs when an arthropod vector supports the life cycle of pathogens inside of its body. The pathogens are transmitted via bites and are also called “active transport” of pathogens.
Biological Vector Transmission
_______ is an infection acquired in the hospital/clinical environment.
Healthcare-Associated Infections
Improperly cleaned healthcare settings and weakened immune status of the host are _______.
Sources of Healthcare-Associated Infections
_______ occur from improper sterilization of surgical equipment.
Surgical Site Infections
______ can happen from contaminated respiratory devices.
Pneumonia
_________ can happen from contaminated equipment from GI surgery.
C. difficile Infections
surgical wounds are caused by _______.
Staphylococcus aureus
diarrhea after abdominal surgery is caused by _________.
Clostridium difficile
_________ collects and analyzes epidemiological information in the United States.
CDC
________ is the number of people or incidence of a specific notifiable disease.
Morbidity
________ is the number of deaths from notifiable disease.
Mortality
________ are diseases in which physicians are required by law to report the occurrence to the CDC.
Nationally Notifiable Infectious Disease
Gonorrhea, HIV infection, and Syphilis are all examples of ________.
Nationally Notifiable Infectious Disease