Chapter 15 - Intracellular Compartments Flashcards
How do cells carry out multiple reactions concurrently that are mutually incompatible?
Require isolated environments for incompatible reactions. Recall, membranes are good selectively permeable barriers in providing these environments.
Eukaryotic cells are able to compartmentalize cellular functions within what?
Organelles
What do organelles do?
1) Enhance local concentration of reactants and enzymes - allowing chemicals to be concentrated and chemical reactions to proceed more efficiently.
2) Provide isolated environments.
3) Enable specialized but mutually incompatible processes to occur simultaneously without interfering with each other.
Each organelle contains a unique set of ___ and ___ molecules and carry out ___ functions.
large, small, specialized
Cytosol
Contains many metabolic pathways, protein synthesis, and the cytoskeleton.
Nucleus
Contains main genome; DNA and RNA synthesis.
Endoplasmic Reticulum (ER)
Synthesis of most lipids; synthesis of proteins for distribution to many organelles and to the plasma membrane.
Lysosomes
Intracellular degradation
Endosomes
Sorting of endocytosed material.
Mitochondria
ATP synthesis by oxidative phosphorylation.
Chloroplasts (in plant cells)
ATP synthesis and carbon fixation by photosynthesis.
Peroxisomes
Oxidation of toxic molecules.
Which organelle houses and protects genetic information?
Nucleus.
(T/F) The nucleus contains main genome and is the site of DNA and RNA synthesis.
True.
Does the nucleus have a double membrane?
Yes, in the form of a nuclear envelope.
In a nucleus, the ___ membrane is continuous with the ___.
outer, ER membrane.
The nucleus ___ with the ___ via nuclear pores embedded in the envelope.
communicates, cytosol.
How many kinds of endoplasmic reticular exist?
Two, rough and smooth ER.
Rough ER
Characterized by ribosomes attached to the cytosolic side (outer surface) of the membrane and usually forms large flattened sheets.
Smooth ER
ER without ribosomes attached and generally forms tubular structures.
Ribosomes
a minute particle consisting of RNA and associated proteins, found in large numbers in the cytoplasm of living cells. They bind messenger RNA and transfer RNA to synthesize polypeptides and proteins.
Microsomes
Broken fragments of ER that spontaneously form sealed vesicles upon homogenization of cells/tissues.
The rough ER is involved in the ___ and ___ of proteins.
Biosynthesis, processing
What is the rough ER responsible for?
Synthesizing both membrane-bound and soluble proteins.
The rough ER is the site for the initial steps of ___.
protein glycosylation.
Protein Glycosylation
Site of addition of preassembled carbohydrate trees to lumenal and transmembrane proteins.