chapter 15 Flashcards

1
Q

central dogma

A

cells are governed by chain of command: DNA->RNA-> protein

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2
Q

gene expression

A

taking genetic information and making proteins

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3
Q

does DNA ever leave the nucleus in eukaryotic cell?

A

no, it stays in the nucleus

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4
Q

mRNA

A

a copy of the information from the gene, coding for protein(s)

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5
Q

RNA processing

A

introns are cut out , and exons exit the nucleus

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6
Q

primary transcript

A

initial RNA transcript before processing , includes introns

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7
Q

5 prime GTP cap

A

tells you what the protein was made for, right before untranslated region

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8
Q

exons

A

information to make protein

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9
Q

poly-A tail

A

holds no information, slows down the degradation of mRNA that start from 3’ tail, protects mRNA from degrading enzymes for a short time

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10
Q

mRNA is long term or short term

A

short term

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11
Q

where do enzymes start chewing the RNA

A

the poly A tail

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12
Q

when mRNA is degraded the nucleotide is

A

reused

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13
Q

amino acids are coded for by

A

nucleotides

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14
Q

start codon

A

AUG methinanine

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15
Q

how long are “words” in genetics

A

3 letters

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16
Q

UUU codes for

A

phenylalanine

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17
Q

CGA codes for

A

arginine

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18
Q

DNA holds the information to make…

A

proteins

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19
Q

transcription

A

synthesis of RNA using info from DNA, produces mRNA

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20
Q

translation

A

synthesis of polypeptide from mRNA

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21
Q

ribosomes are the sight of…

A

translation

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22
Q

translation

A

synthesis of the polypeptide from mRNA

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23
Q

template strand

A

template for ordering the sequence of complementary nucleotides

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24
Q

which way are codons read?

A

5 prime to 3 prime

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25
non-template strand ( coding strand)
nucleotides are identical to codons, T is present in DNA instead of U in RNA
26
how many amino acids can the body have?
20 amino acids
27
codon specifies for...
amino acid
28
how many different types of codons
64 triplets, 61 code for amino acids and 3 triplets are signals to send translation
29
in translation what does mRNA code for?
amino acids
30
UAG, UAA, UGA code for
termination/ stop codons
31
initiation of transcription
separates DNA strands, has promoter, DNA tells where RNA polymerase can bind and start
32
elongation
RNA polymerase adds complementary nucleotides AUGC to make mRNA
33
termination
when RNA reaches the end and jumps off
34
how does transcription and translation relate in prokaryotes
there's no separation because of the lack of a nuclear membrane
35
what does the ribosome jump onto to start translation
start codon
36
RNA synthesis is catalyzed by
RNA polymerase
37
RNA polymerase
pries DNA apart and joins together the RNA nucleotides , does not need primer
38
RNA synthesis
substitutes U for T in ACTG
39
promoter
signals where transcription starts
40
TATA box in the initiation
where the promoter is and where to attach sends a molecular, form initiation complex
41
transcription factors
tell what body part to code for
42
transcription initiation complex
RNA polymerase II and promoter binding together
43
why is there a leading and lagging strand
lagging strand back stitched because the enzyme needs to be read 5' to 3'
44
in prokaryotes do ribosomes wait to jump on?
no they jump on even when synthesis is not done
45
what does the nucleosome have to do to be used
has to be unpacked , so polymerase can make mRNA
46
RNA splicing carried out by...
introns cut out, exons spliced together , catalyzed by spliceosomes
47
spliceosomes
variety of proteins and small RNA that recognize splice sites, at 5' and end of 3'
48
transfer RNA
enters ribosome, compliments codon, transfers 1 amino acid
49
polypeptide chain
leaked out of the ribosome
50
protein synthesis
decodes mRNA to make polypeptide,
51
polypeptide
formed from amine having a carboxyl bond with another amino acid. catalyzed by ribosomes
52
translation initiation
mRNA attaches to ribosome, AUG start codon, tRNA appropriate anticodon attaches
53
translation elongation
tRNA's move in with appropriate amino acid
54
translation termination
stop codon is reached, amino acid chain is released to be processed
55
ribozymes
RNA molecules enzymes, can splice RNA
56
RNA can be folded to
have many functions
57
domains in protein
specific info to make protein
58
tRNA enables translation of mRNA codon to..
to amino acid
59
anticodon
pairs w complementary codon
60
steps of translation
1. match tRNA and amino acid, and tRNA anticodon to mRNA codon
61
p site
carries growing protein
62
a site
carries next amino acid to be added to chain
63
e site
exit site discharged tRNAs leave ribosome