Chapter 14 Mendel and the Gene Idea Flashcards

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1
Q

A red bull is crossed with a white cow and all of the offspring are roan, an intermediate color that is caused by the presence of both red and white hairs. This is an example of genes that are __________.

A

codominant

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2
Q

Mendel’s law of segregation states that __________.

A

the two alleles for a heritable character segregate (separate from each other) during gamete formation and end up in different gametes

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3
Q

In a typical pea experiment, two true-breeding plants with distinct traits of a single character are called the __________, and the offspring are called the __________, which will always be __________.

A

P (or parental) generation; F1 (or first filial) generation; hybrid

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4
Q

Huntington’s disease is an example of a genetic disorder caused by __________.

A

a lethal dominant allele that afflicts an individual later in life

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5
Q

Human ABO groups are best described as an example of __________.

A

multiple alleles

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6
Q

What kind of protection does the Genetic Information Nondiscrimination Act of 2008 provide the public with regard to the use of genetic information?

A

The law prohibits the use of genetic test information to deny insurance coverage or employment to individuals.

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7
Q

If a plant variety is true-breeding for a dominant trait, then __________.

A

if the plant were allowed to self-pollinate, all of the progeny would have the dominant trait

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8
Q

Achondroplasia, a type of dwarfism, and Huntington’s disease are examples of __________, with the exception that the Huntington’s allele is __________.

A

dominant inherited disorders; lethal

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9
Q

Besides the fact that pea plants have a short generation time, the key to Mendel’s successful plant-breeding experiments was that pea plants usually __________.

A

self-pollinate

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10
Q

Mendel studied __________, heritable features that vary among individuals; each variant is called a __________.

A

characters; trait

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11
Q

An alternative version of a gene is called a(n) __________.

A

allele

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12
Q

In addition to the ABO system, humans have other blood groups, including the MN system. Individuals who have alleles for both M and N show __________ for the M and N red blood cell surface antigens.

A

codominance

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13
Q

Pea plants are tall if they have the genotype TT or Tt, and they are short if they have genotype tt. A tall plant is mated with a short plant. Which outcome below would indicate that the tall parent plant was heterozygous?

A

The ratio of tall offspring to short offspring is 1:1

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14
Q

Which choice below is a basic difference between Mendel’s particulate hypothesis and the hypothesis of blending inheritance?

A

The blending inheritance hypothesis, but not the particulate hypothesis, maintained that after a mating, the genetic material provided by each of the two parents is mixed in the offspring, losing its individual identity.

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15
Q

The effect of the environment on a phenotype is referred to as __________.

A

multifactorial

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16
Q

In Labrador retrievers, a dog that has the genotype BBee, where BB produces black-pigmented fur and ee produces yellow-pigmented fur, would have __________ fur and would exhibit __________.

A

yellow; epistasis

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17
Q

In people with sickle-cell disease, red blood cells break down, clump, and clog the blood vessels. The blood vessels and the broken cells accumulate in the spleen. Among other things this leads to physical weakness, heart failure, joint pain, and brain damage. Such a suite of symptoms can be explained by __________.

A

the pleiotropic effects of the sickle-cell allele

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18
Q

If a heterozygous plant is allowed to self-pollinate, what proportion of the offspring will also be heterozygous?

A

1/2

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19
Q

If an organism that is homozygous dominant is crossed with a heterozygote for that trait, the offspring will be __________.

A

all of the dominant phenotype

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20
Q

The F1 generation differed from the F2 in Mendel’s experiments in that __________.

A

all of the F1 showed the dominant phenotype, but only three-fourths of the F2 did

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21
Q

In incomplete dominance, the offspring __________.

A

will have an appearance that’s intermediate between those of the two parental types

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22
Q

The term “true-breeding plants” means __________.

A

that self-pollinating plants will always produce the same trait of a particular character

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23
Q

A man who can roll his tongue and a woman who cannot roll her tongue have a son who can roll his tongue (R = can roll tongue; r = can’t roll tongue). The son is curious about whether his father is homozygous or heterozygous for the tongue-rolling trait. Which of the following facts would allow him to know?

A

His father’s mother cannot roll her tongue.

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24
Q

If the two traits that Mendel looked at in his dihybrid cross of smooth yellow peas with wrinkled green peas had been controlled by genes that were located near each other on the same chromosome, then the F2 generation __________.

A

would have deviated from the 9:3:3:1 phenotypic ratio that is predicted by the law of independent assortment

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25
Q

A family tree that describes traits in families is called a __________.

A

pedigree analysis

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26
Q

Human blood groups are governed by three alleles, IA, IB, and i. IA and IB are codominant and i is recessive to both. A man who has type B blood and a woman who has type A blood could have children of which of the following phenotypes?

A

A, B, AB, or O

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27
Q

Color in squash is controlled by epistatic interactions in which color is recessive to no color. At the first locus white squash (W) is dominant to colored squash (w). At the second locus yellow (Y) is dominant to green (y). What is the phenotype of a squash with the genotype wwYy?

A

Yellow

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28
Q

Fetal cells may be removed along with fluid from the womb by a process known as __________.

A

amniocentesis

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29
Q

__________ occurs when a single gene affects the phenotype of many characters in an individual.

A

A pleiotropic effect

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30
Q

The law of segregation states that the _____ for a particular character segregate during gamete formation.

A

Alleles

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31
Q

A _____ trait is expressed in an organism with one or two copies of the allele.

A

Dominant

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32
Q

A _____trait is expressed only if an organism has two copies of the same allele.

A

Recessive

33
Q

An individual organism with two of the same allele for a particular character is _____.

A

Homozygous

34
Q

An individual organism with two different alleles for a particular character is _____.

A

Heterozygous

35
Q

An individual’s _____ describes which alleles are present at a specific gene locus.

A

Genotype

36
Q

An individual’s _____ describes which trait is expressed.

A

phenotype

37
Q

To determine which allele is dominant, it is necessary to perform multiple matings of the two parents.
Reset the simulation and make sure wild-type is selected for both parents.
Run the simulation five times so that you get a larger data set. (Do not reset the simulation in between runs.)
Record the data in a table, or take a screenshot of the data table in the simulation.
Reset the simulation and select apterous for both parents.
Run the simulation five times so that you get a larger data set. (Do not reset the simulation in between runs.)
Compare the data from the apterous ×
apterous cross to the data from the wild-type ×
wild-type cross.
Which trait is dominant and how do you know?

A

Wild-type wings are dominant because wild-type parents can produce apterous offspring, but apterous parents can’t produce wild-type offspring.

38
Q

Now that you have determined which traits are dominant and recessive, you will use that information to determine the genotypes of the parents in a specific mating. Typically, alleles are identified using single letters, with uppercase letters representing the dominant allele and lowercase letters representing the recessive allele. You will use A
as the wild-type wing allele and a
as the apterous wing allele.
Reset the simulation and select wild-type for both parents.
Run the simulation five times so that you get a larger data set. (Do not reset the simulation in between runs.)
What are the genotypes of each parent?

A

Both the male and female are Aa
.

39
Q

Now that you have determined the most likely genotypes that correspond to each phenotype, you will predict the results of a different mating. Suppose one parent is wild-type and the other is apterous. Using a Punnett square, set up this cross and predict the ratio of phenotypes.
What phenotypic ratio do you predict?

A

1:1

40
Q

Now test your prediction using the simulation.
Reset the simulation and select wild-type for one parent and apterous for the other parent.
Run the simulation five times. (Do not reset the simulation in between runs.)
Was your prediction of a 1:1 phenotypic ratio confirmed?

A

Yes, the ratio of wild-type to apterous offspring was approximately 1:1 across all five runs.

41
Q

Albinism is a recessive condition in which homozygous individuals have decreased production of melanin in their skin, eyes, and hair. Individuals who are homozygous dominant or heterozygous exhibit normal melanin production.

Suppose two people are heterozygous at this gene locus. They decide to have children and want to know what the chances are of their children having albinism. Using a Punnett square, set up this cross and predict the ratio of phenotypes.

What phenotypic ratio do you predict?

A

3:1

42
Q

Because the inheritance pattern for albinism is the same as for Drosophila wings, you can use the simulation to test predictions about the human albinism trait.
Reset the simulation to its default settings. The wild-type flies are equivalent to the parents who are heterozygous for albinism.
Run the simulation five times without resetting between runs.
Was your prediction of a 3:1 phenotypic ratio confirmed?

A

Yes, the ratio of unaffected to albino offspring was approximately 3:1 across all five runs.

43
Q

How could the botanist best determine whether the genotype of the green-pod plant is homozygous or heterozygous?

A

Cross the green-pod plant with a yellow-pod plant.

44
Q

Suppose that the botanist carried out the test cross described in Parts A and B and determined that the original green-pod plant was heterozygous (Gg). Which of Mendel’s findings does her test cross illustrate?

A

law of segregation

45
Q

During which part of meiosis (meiosis I or meiosis II) do the two alleles of a gene separate? During which phase does the separation occur?

A

meiosis 1, anaphase

46
Q

Which of the following statements correctly describes the terms monohybrid cross and dihybrid cross?

A

A monohybrid cross involves a single parent, whereas a dihybrid cross involves two parents.

47
Q

How many unique gametes could be produced through independent assortment by an individual with the genotype AaBbCCDdEE?

A

8

48
Q

Which of the following describes why Mendel continued some of his experiments into the F2 or F3 generation?

A

Data from the F1 generation did not allow him to distinguish which alleles were segregating

49
Q

Which of the following statements about the law of independent assortment is correct?

A

It describes the inheritance of different genes relative to one another.

50
Q

Which of the following statements about the law of segregation is correct?

A

It describes the inheritance of different alleles relative to one another.

51
Q

A diploid animal is dihybrid at the Head shape (H) and Tail length (T) loci. Which of the following gamete genotypes can it produce?

A

HhTt

52
Q

Which of the following statements correctly describes how Mendel explained why traits disappeared in the F1 generation and then reappeared in the F2 generation?

A

Traits can be dominant or recessive, and the recessive traits were “hidden” by the dominant ones in the F1.

53
Q

When Mendel set up a Parental (P) cross between true breeding purple and white flowered plants to generate the F1 and then allowed the F1 to self-pollinate to generate the F2 he saw a dominant to recessive ratio of 3:1. What phenotypic ratio would be expected if he crossed the F1 with the original purple parent?

A

4:0

54
Q

Which of the following statements correctly explains the fact that all seven of the pea plant traits studied by Mendel obeyed the principle of independent assortment?

A

All of the genes controlling the traits behaved as if they were on different chromosomes

55
Q

Why did all of the F1 offspring of Mendel’s purple and white flowered pea cross always look like one of the two parental varieties?

A

One allele was dominant.

56
Q

Mendel crossed true breeding yellow-seeded and green-seeded pea plants and then allowed the offspring to self-pollinate to produce an F2 generation. The results were as follows: 6,022 yellow and 2,001 green (8,023 total). Which of the following statements correctly describes the relationship of the allele for green seeds to the allele for yellow seeds?

A

The green allele is recessive to the yellow allele.

57
Q

Albinism is a recessive trait where an individual does not produce the pigment melanin. A man and woman both produce melanin, but both have one parent with albinism. What is the probability that their first child will have albinism?

A

1/4

58
Q

Albinism is a recessive trait where an individual does not produce the pigment melanin. A man and woman who both produce melanin have one child out of three who has albinism. What are the genotypes of the man and woman?

A

Both parents must be heterozygous.

59
Q

A brown dog crossed with a yellow dog produced 12 brown offspring. A second brown individual was obtained. When the yellow dog was crossed with this animal, six brown and six yellow offspring were born. Which of the following best explains the results of the second cross?

A

yellow is a recessive trait; brown is a dominant trait

60
Q

In a particular plant, green seed color is dominant to blue. If two plants with green seeds were crossed and resulted in 302 green and 98 blue seed plants, what was the most probable genotype of each parent?

A

Gg × Gg

61
Q

When Mendel crossed yellow-seeded and green-seeded pea plants, all the offspring were yellow-seeded. Which of the following genotypic ratios was expected when Mendel crossed the F1 yellow-seeded plants with green-seeded plants?

A

1:1

62
Q

Pea plants produce either purple or white flowers with purple showing complete dominance. A gardener was given plants with purple flowers. Which of the following types of crosses would best allow her to determine the genotype of her plant in one generation?

A

A testcross

63
Q

In pea plants, the tall phenotype is dominant to the dwarf phenotype. If a heterozygous pea plant is crossed with a homozygous tall pea plant, what is the probability that the offspring will be dwarf in size?

A

0

64
Q

Two true-breeding stocks of pea plants are crossed. One parent has red, axial flowers, and the other has white, terminal flowers; all F1 individuals have red, axial flowers. Among the F2 offspring, what is the probability of producing plants with white axial flowers?

A

3/16

65
Q

Having polydactyly (extra digits on hands and feet) is a dominant trait. A man has polydactyly. His wife and oldest daughter do not have polydactyly. The couple’s second child has polydactyly. What is the probability that their next (third) child will have extra digits?

A

1/2

66
Q

In cattle, roan coat color (mixed red and white hairs) occurs in the heterozygous (CRCW) offspring of red (CRCR) and white (CWCW) homozygotes. Which of the following crosses would produce offspring in the ratio of 1 red:2 roan:1 white?

A

roan × roan

67
Q

A radish is a root vegetable that produces flowers that may be red, purple, or white. A cross between a red-flowered plant and a white-flowered plant yields all-purple offspring. The part of the radish we eat may be oval or long, with long being the dominant trait. If true-breeding red-flowered, long radishes long radishes are crossed with true-breeding white oval radishes, the F1 will be expected to exhibit which of the following phenotypes?

A

purple and long

68
Q

Black fur in mice (B) is dominant to brown fur (b). Short tails (S) are dominant to long tails (s). What fraction of the progeny of crosses BbSs × BBss will be expected to have black fur and long tails?

A

1/16

69
Q

Ten plants of the same genotype are planted in a large flower garden. Later that year, some of the ten plants have blue flowers and others have pink flowers. This can be best explained by which of the following statements?

A

environmental factors such as soil pH affect the phenotype

70
Q

Radish flowers may be red, purple, or white. A cross between a red-flowered plant and a white-flowered plant yields all-purple offspring. The flower color trait in radishes is an example of which of the following inheritance patterns?

A

incomplete dominance

71
Q

Gene S controls the sharpness of spines in a type of cactus. Cacti with the dominant allele, S, have sharp spines, whereas homozygous recessive ss cacti have dull spines. Also, a second gene, N, determines whether or not cactuses have spines. Homozygous recessive nn cactuses have no spines at all. What phenotypes would be expected from a cross between a true-breeding sharp-spined cactus and a spineless cactus?

A

all sharp-spined progeny

72
Q

Gene S controls the sharpness of spines in a type of cactus. Cacti with the dominant allele, S, have sharp spines, whereas homozygous recessive ss cacti have dull spines. A second gene, N, determines whether or not cactuses have spines. Homozygous recessive nn cactuses have no spines at all. Which of the following explain why a crossing a true breeding spineless cactus with a dull-spined cactus could result in both sharp- and dull-spined offspring?

A

The spineless cactus was heterozygous at the S locus

73
Q

In human blood types, Rh positive is a trait that shows simple dominance over Rh negative. The Rh phenotype is recorded by stating “positive” or “negative” after the individuals ABO blood type. A woman who has blood type A positive has a daughter who is type O positive and a son who is type B negative. Which of the following phenotypes is possible for the father?

A

B positive

74
Q

In rabbits, the homozygous genotype LCLC has straight legs, LCLc results in deformed legs, and LcLc results in very short legs. The genotype FBFB produces black fur, FBFb brown fur, and FbFb white fur. If a cross is made between brown rabbits with deformed legs and white rabbits with deformed legs, what percent of the offspring would be expected to have deformed legs and white fur?

A

25%

75
Q

Which of the following statements correctly explains the observation that parents with two different phenotypes produced offspring with a phenotype that is a blend of the two parental varieties?

A

Neither of the parental alleles is dominant over the other

76
Q

An obstetrician knows that her patient’s fetus is at risk for a serious disorder that is detectable biochemically in fetal cells. The obstetrician would most reasonably offer which of the following procedures to her patient?

A

amniocentesis or CVS

77
Q

Phenylketonuria (PKU) is a recessive human disorder in which an individual cannot appropriately break down the amino acid phenylalanine. This amino acid is not naturally produced by humans. Which of the following treatments would be most effective for people with PKU?

A

Regulate the individual’s diet to severely limit the uptake of phenylalanine.

78
Q

Hutchinson-Gilford progeria is an exceedingly rare human genetic disorder in which individuals look very old even as young children, experience very early senility and severe coronary artery disease, and have a life expectancy of 13 years. Which of the following statements represents the most likely assumption regarding this disorder?

A

The disorder may be due to mutation in a single protein-coding gene.