Chapter 14: Epidemiology Flashcards
human microbiome
microrgansims in the body
normal flora/ microbiome
healthy microrganisms in the body
probiotics
healthy microrganisms introduced into the body
symbiosis
mutualism
commensalism
parasitism
symbiosis- interaction of species with one another
mutualism- both organisms benefit
commensalism- one benefits where the other is unaffected
parasitism- one benefits where the other is harmed
oppertunistic pathogens
normal microbiota becoming pathogenic ex E.coli
microbial antagonism
competition between microbes
Koch’s postulates
1) pathogen present in every case of disease
2) pathogen isolated from the diseased host and grown in pure culture
3) pathogen must cause disease in healthy animal
4) pathogen must be shown to be the orignal pathogen
Exceptions to Koch’s postulates
- some pathogens cause multiple signs and symptoms (hard to trace signs and symptoms to microbes, ex. strep throat)
- diseases can be caused by multiple pathogens (hard to identify original pathogen, ex. pneumonia)
-some pathogens can’t be grown in pure culture (ex. sphyillis) - some pathogens only infect humans (difficult to test for cause because it is unethical, ex. small pox)
incidence number
number of people n a population who develop a disease during a time period
prevalance number
number of people who develop a disease at a specified time
acute disease
develops rapidly but lasts a short time (influenza)
latent infection
agent remains inactive until it produces symptoms (cold sores)
chronic infection
develops more more slowly for a longer time (cancer)
slow infection
progressively worse over time (mad cow disease)
local infection
pathogen limited to a small area (acne)