Chapter 14 - Cardiovascular Flashcards

1
Q

primary function of the CV system

A

transport of nutrients, water, gases, wastes, and chemical signals to and from all parts of the body

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2
Q

blood flows down a ____

A

pressure gradient (delta P)

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3
Q

driving pressure for blood flow

A

the pressure created when the ventricles contract

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4
Q

resistance of a fluid flowing through a tube increases as the length of the tube and the viscosity of the fluid ___ and as the radius of the tube ___

A

increase; decrease

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5
Q

fluid flow through a tube is ___ to the pressure gradient

A

proportional

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6
Q

flow rate

A

the volume of blood that passes one point in the system per unit time

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7
Q

velocity

A

the distance a volume of blood travels in a given period of time

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8
Q

at a constant flow rate, the velocity of flow through a small tube is ___ than the velocity through a larger tube

A

gaster

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9
Q

autorhythmic cells

A

noncontractile myocardium. the signal for contraction originates here

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10
Q

intercalated disks

A

link myocardial cells. contain gap junctions. the junctions allow depolarization to spread rapidly from cell to cell

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11
Q

calcium-induced calcium release

A

in contactile cell excitation-contraction coupling, an action potential opens Ca2+ channels. Ca2+ entry into the cell triggers the release of additional Ca2+ from the sarcoplasmic reticulum through calcium-induced calcium release

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12
Q

the force of cardiac muscle contraction can be graded according to

A

how much Ca2+ enters the cell

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13
Q

the action potentials of myocardial contractile cells have a rapid depolarization phase created by ___ influx, and a steep repolarization phase d/t ___ efflux. the action potential also has a plateau phase created by ___ influex

A

Na+; K+; Ca2+

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14
Q

pacemaker potential

A

an unstable membrane potential in autorhythmic cells. it is d/t If channels that allow net influx of positive charge

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15
Q

the steep depolarization phase of the autorhythmic cell action potential is caused by ___ influx. the repolarization phase is f/t ___ efflux

A

Ca2+; K+

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16
Q

electrical pathway through the heart

A

SA node -> AV node -> bundle of His (AV bundle) -> bundle branches -> Purkinje fibers -> myocardial contractile cells

17
Q

What sets the pace of the heartbeat?

A

the SA node. if the SA node malfunctions, other autorhythmic cells in the AV node or ventricles take control of HR

18
Q

ECG

A

surface recording of the electrical activity of the heart; provides info on heart rate and rhythm, conduction velocity, and the condition of cardiac tissues

19
Q

P wave

A

represents atrial depolarization

20
Q

QRS complex

A

represents ventricular depolarization; atrial repolarization is incorporated in the QRS complex

21
Q

T wave

A

represents ventricular repolarization

22
Q

most blood enters the ventricles when…

A

the atria are relaxed. only 20% of ventricular filling at rest it d/t atrial contraction

23
Q

the first heart sound is d/t

A

the closure of the AV valves during ventricular contraction

24
Q

the second heart sound is d/t

A

the semilunar valves closing when ventricles relax and ventricular pressure falls

25
Q

isovolumic ventricular contraction

A

ventricular blood volume does not change but pressure rises

26
Q

stroke volume

A

the amount of blood pumped by one ventricle during one contraction

27
Q

cardiac output

A

the volume of blood pumped per ventricle per unit time. it is equal to HR x stroke volume. the avg CO at rest is 5 L/min

28
Q

homeostatic changes in cardiac output are accomplished by varying:

A

HR, stroke volume, or both

29
Q

___ activates ___ receptors to hyperpolarize pacemakers

A

ACh; muscarinic

30
Q

the longer a muscle fiber is when it begins to contract, the ___ the force of contraction

A

greater

31
Q

the Frank-Starling law of the heart says that an increase in end-diastolic volume (EDV) results in a ___ stroke volume

A

greater

32
Q

end-diastolic volume (EDV)

A

the maximum volume of blood that the ventricles hold during a cardiac cycle

33
Q

end-systolic volume (ESV)

A

the amount of blood left in the ventricle at the end of contraction

34
Q

preload

A

the degree of myocardial stretch created by venous return

35
Q

afterload

A

the combined load of blood in the ventricle (the EDV) and arterial resistance during ventricular contraction. AKA the load placed on the ventricle as it contracts. it reflects the preload and the effort required to push the blood out of the arterial system. mean arterial pressure is a clinical indicator of afterload

36
Q

ejection fraction

A

the percentage of EDV ejected w/ one contraction (stroke volume/EDV). used to evaluate ventricular function

37
Q

mean arterial pressure (MAP

A

average blood pressure in the arteries, estimated as diastolic pressure plus 1/3 of the pulse pressure. a clinical indicator of afterload.